Challenges and opportunities of functionalized cucurbiturils for biomedical applications

H Yin, Q Cheng, D Bardelang, R Wang - JACS Au, 2023 - ACS Publications
Cucurbit [n] uril (CB [n]) macrocycles (especially CB [5] to CB [8]) have shown exceptional
attributes since their discovery in 2000. Their stability, water solubility, responsiveness to …

Cucurbituril-based molecular recognition

SJ Barrow, S Kasera, MJ Rowland, J Del Barrio… - Chemical …, 2015 - ACS Publications
The product of the condensation reaction between glycoluril and formaldehyde was first
reported in a thesis by Eberhard Meyer in 1904 (1) and then published by Behrend and co …

Protein assembly: versatile approaches to construct highly ordered nanostructures

Q Luo, C Hou, Y Bai, R Wang, J Liu - Chemical Reviews, 2016 - ACS Publications
Nature endows life with a wide variety of sophisticated, synergistic, and highly functional
protein assemblies. Following Nature's inspiration to assemble protein building blocks into …

Modulators of protein–protein interactions

LG Milroy, TN Grossmann, S Hennig… - Chemical …, 2014 - ACS Publications
Since Hedin's characterization of trypsin and antitrypsin in 1906,(1) arguably the first
account of a regulatory protein–protein interaction (PPI), contemporary understanding of …

Supramolecular chemistry targeting proteins

S van Dun, C Ottmann, LG Milroy… - Journal of the American …, 2017 - ACS Publications
The specific recognition of protein surface elements is a fundamental challenge in the life
sciences. New developments in this field will form the basis of advanced therapeutic …

Functional interlocked systems

SFM van Dongen, S Cantekin… - Chemical Society …, 2014 - pubs.rsc.org
With the advent of supramolecular chemistry and later nanotechnology a great deal of
research has been focused on new types of molecular structures, which are not held …

Supramolecular free radicals: near-infrared organic materials with enhanced photothermal conversion

Y Jiao, K Liu, G Wang, Y Wang, X Zhang - Chemical science, 2015 - pubs.rsc.org
A novel kind of supramolecular free radical with significantly improved free radical yield and
enhanced near-infrared (NIR) photothermal conversion has been fabricated. Perylene …

[HTML][HTML] Recent advances in supramolecular antidotes

H Yin, X Zhang, J Wei, S Lu, D Bardelang, R Wang - Theranostics, 2021 - ncbi.nlm.nih.gov
Poisons always have fascinated humankind. Initially considered as deleterious or
hazardous substances, the modern era has witnessed the controlled utilization of dangerous …

Functional protein nanostructures: a chemical toolbox

SL Kuan, FRG Bergamini, T Weil - Chemical Society Reviews, 2018 - pubs.rsc.org
Nature has evolved an optimal synthetic factory in the form of translational and
posttranslational processes by which millions of proteins with defined primary sequences …

Construction of protein nanowires through cucurbit [8] uril‐based highly specific host–guest interactions: an approach to the assembly of functional proteins

C Hou, J Li, L Zhao, W Zhang, Q Luo… - Angewandte Chemie …, 2013 - Wiley Online Library
Protein nanostructures are of great interest in the field of bionics, owing not only to their
biocompatible and biodegradable properties, but also to their high structural durability …