The integrate-and-fire neuron model is one of the most widely used models for analyzing the
behavior of neural systems. It describes the membrane potential of a neuron in terms of the …

For years we have known that cortical neurons collectively have synchronous or oscillatory
patterns of activity, the frequencies and temporal dynamics of which are associated with …

To investigate the basis of the fluctuating activity present in neocortical neurons in vivo, we
have combined computational models with whole-cell recordings using the dynamic-clamp …

Functional neurosurgery in patients with movement disorders has provided a unique
opportunity to record directly form the human basal ganglia (BG) and to thereby further our …

It has been empirically established that the cerebral cortical areas defined by Brodmann one
hundred years ago solely on the basis of cellular organization are closely correlated to their …

In vivo, in vitro and computational studies were used to investigate the impact of the synaptic
background activity observed in neocortical neurons in vivo. We simulated background …

How does the brain work? After a century of research, we still lack a coherent view of how
neurons process signals and control our activities. But as the field of computational …

The visual cortex responds to repeated presentations of the same stimulus with high
variability. Because the firing mechanism is remarkably noiseless, the source of this …

Neuronal Noise combines experimental, theoretical and computational results to show how
noise is inherent to neuronal activity, and how noise can be important for neuronal …

Pairwise correlations among spike trains recorded in vivo have been frequently reported. It
has been argued that correlated activity could play an important role in the brain, because it …