Triggered chemiluminescence emission of spiroadamantane-1, 2-dioxetanes to detect
bioanalytes has fueled the emerging popularity of chemiluminescence imaging in live …

De novo enzyme design has sought to introduce active sites and substrate-binding pockets
that are predicted to catalyse a reaction of interest into geometrically compatible native …

Organoid models have been used to address important questions in developmental and
cancer biology, tissue repair, advanced modelling of disease and therapies, among other …

Molecularly generated light, referred to here as “molecular light”, mainly includes
bioluminescence, chemiluminescence, and Cerenkov luminescence. Molecular light …

Multiplex optical detection in live cells is challenging due to overlapping signals and poor
signal‐to‐noise associated with some chemical reporters. To address this, the application of …

The expansion of fluorescence bioimaging toward more complex systems and geometries
requires analytical tools capable of spanning widely varying timescales and length scales …

Introduction Luminescence-based technologies, specifically bioluminescence and
chemiluminescence, are powerful tools with extensive use in drug discovery. Production of …

Incorporating non-invasive biosensing features in organ-on-chip models is of paramount
importance for a wider implementation of these advanced in vitro microfluidic platforms …

Bioluminescent tools can illuminate cellular features in whole organisms. Multi-component
tracking remains challenging, though, owing to a lack of well-resolved probes and long …

Bioluminescence imaging has become a valuable tool in biological research, offering
several advantages over fluorescence-based techniques, including the absence of …