There are numerous extra-and intra-cellular processes involved in the production of reactive
oxygen species (ROS). Augmented ROS generation can cause the damage of biomolecules …

The management of patients with autoimmune rheumatic diseases such as rheumatoid
arthritis (RA) remains a significant challenge. Often the rheumatologist is restricted to …

Rheumatoid arthritis (RA) is an inflammatory disease that begins with a loss of tolerance to
modified self-antigens and immune system abnormalities, eventually leading to synovitis …

Antigen presentation is in the center of the immune system, both in host defense against
pathogens, but also when the system is unbalanced and autoimmune diseases like multiple …

Rheumatoid arthritis (RA) affects the joints and extra‐articular organs and poses a
significant health care problem in the modern era. Although current standard treatment …

Autoantibodies have been associated with human pathologies for a long time, particularly
with autoimmune diseases (AIDs). Rheumatoid factor (RF) is known since the late 1930s to …

Tissue inflammation results in the production of numerous reactive oxygen, nitrogen and
chlorine species, in addition to the products of lipid and sugar oxidation. Some of these …

Objective To assess the prevalence of anti–carbamylated protein (anti‐CarP) antibodies in a
French cohort of patients with early arthritis and to investigate their association with clinical …

The presence of a disease continuum in inflammatory arthritis (IA) is a recognised concept,
with distinct stages from at-risk stage (presence of anti citrullinated-peptide autoantibody) to …

The chronic debilitating lung disease, idiopathic pulmonary fibrosis (IPF), is characterized by
a progressive decline in lung function, with a median mortality rate of 2–3 years after …