Unveiling microbial diversity: harnessing long-read sequencing technology

DP Agustinho, Y Fu, VK Menon, GA Metcalf… - Nature …, 2024 - nature.com
Long-read sequencing has recently transformed metagenomics, enhancing strain-level
pathogen characterization, enabling accurate and complete metagenome-assembled …

Genome-resolved metagenomics: a game changer for microbiome medicine

N Kim, J Ma, W Kim, J Kim, P Belenky… - Experimental & Molecular …, 2024 - nature.com
Recent substantial evidence implicating commensal bacteria in human diseases has given
rise to a new domain in biomedical research: microbiome medicine. This emerging field …

Globally distributed Myxococcota with photosynthesis gene clusters illuminate the origin and evolution of a potentially chimeric lifestyle

L Li, D Huang, Y Hu, NM Rudling, DP Canniffe… - Nature …, 2023 - nature.com
Photosynthesis is a fundamental biogeochemical process, thought to be restricted to a few
bacterial and eukaryotic phyla. However, understanding the origin and evolution of …

<? mode longmeta?> SPIRE: a Searchable, Planetary-scale mIcrobiome REsource

TSB Schmidt, A Fullam, P Ferretti, A Orakov… - Nucleic Acids …, 2024 - academic.oup.com
Meta'omic data on microbial diversity and function accrue exponentially in public
repositories, but derived information is often siloed according to data type, study or sampled …

Multi-heme cytochrome-mediated extracellular electron transfer by the anaerobic methanotroph 'Candidatus Methanoperedens nitroreducens'

X Zhang, GH Joyce, AO Leu, J Zhao, H Rabiee… - Nature …, 2023 - nature.com
Anaerobic methanotrophic archaea (ANME) carry out anaerobic oxidation of methane, thus
playing a crucial role in the methane cycle. Previous genomic evidence indicates that multi …

proGenomes3: approaching one million accurately and consistently annotated high-quality prokaryotic genomes

A Fullam, I Letunic, TSB Schmidt… - Nucleic acids …, 2023 - academic.oup.com
The interpretation of genomic, transcriptomic and other microbial 'omics data is highly
dependent on the availability of well-annotated genomes. As the number of publicly …

Update on the proposed minimal standards for the use of genome data for the taxonomy of prokaryotes

R Riesco, ME Trujillo - International Journal of Systematic …, 2024 - microbiologyresearch.org
The field of microbial taxonomy is dynamic, aiming to provide a stable and contemporary
classification system for prokaryotes. Traditionally, reliance on phenotypic characteristics …

Primary succession of Bifidobacteria drives pathogen resistance in neonatal microbiota assembly

Y Shao, C Garcia-Mauriño, S Clare, NJR Dawson… - Nature …, 2024 - nature.com
Human microbiota assembly commences at birth, seeded by both maternal and
environmental microorganisms. Ecological theory postulates that primary colonizers dictate …

HiFi metagenomic sequencing enables assembly of accurate and complete genomes from human gut microbiota

CY Kim, J Ma, I Lee - Nature communications, 2022 - nature.com
Advances in metagenomic assembly have led to the discovery of genomes belonging to
uncultured microorganisms. Metagenome-assembled genomes (MAGs) often suffer from …

SemiBin2: self-supervised contrastive learning leads to better MAGs for short-and long-read sequencing

S Pan, XM Zhao, LP Coelho - Bioinformatics, 2023 - academic.oup.com
Motivation Metagenomic binning methods to reconstruct metagenome-assembled genomes
(MAGs) from environmental samples have been widely used in large-scale metagenomic …