T Fu, S Zeng, Q Zheng, F Zhu - Drug Metabolism and Disposition, 2023 - ASPET
The ATP-binding cassette (ABC) and solute carrier (SLC) transporters are critical determinants of drug disposition, clinical efficacy, and toxicity as they specifically mediate …
O Kadioglu, MEM Saeed, M Munder, A Spuller… - Biomedicine & …, 2020 - Elsevier
ATP-binding cassette (ABC) transporters mediate multidrug resistance in cancer. In contrast to DNA single nucleotide polymorphisms in normal tissues, the role of mutations in tumors is …
H Venkata Subbiah, P Ramesh Babu… - Egyptian Journal of …, 2020 - Springer
Abstract Background Single nucleotide polymorphisms (SNPs) play a significant role in differences in individual's susceptibility to diseases, and it is imperative to differentiate …
Single-nucleotide polymorphisms (SNPs) are the most common genetic variations for various complex human diseases, including cancers. Genome-wide association studies …
S Akter, AS Roy, MIQ Tonmoy… - Journal of Biomolecular …, 2022 - Taylor & Francis
In humans, the dimeric receptor complex IFNAR2-IFNAR1 accelerates cellular response triggered by type I interferon (IFN) family proteins in response to viral infection including …
Due to the high prevalence of cancer, progress in the management of cancer is the need of the hour. Most cancer patients develop chemotherapeutic drug resistance, and many remain …
LN Zhang, YZ Xia, C Zhang, H Zhang, JG Luo, L Yang… - Phytomedicine, 2020 - Elsevier
Background Therapeutic failure and drug resistance are common and have important implications in the poor prognosis of advanced breast cancer. It is necessary to acquire a …
S Chatterjee, R Chakraborty… - Journal of Biomolecular …, 2022 - Taylor & Francis
Melanoma is a type of skin cancer. Numerous genes and their proteins are strongly associated with melanoma susceptibility. This study aims to use an in silico method to …
D AHMEDLİ, Z GÜMÜŞ, R YETKİN… - MAS Journal of …, 2024 - masjaps.com
This study investigates the effects of Mentha longifolia L. and the chemotherapeutic drug docetaxel on drug resistance in colon cancer. One of the major challenges in colon cancer …