Thalamic pathology and memory loss in early Alzheimer's disease: moving the focus from the medial temporal lobe to Papez circuit

JP Aggleton, A Pralus, AJD Nelson, M Hornberger - Brain, 2016 - academic.oup.com
It is widely assumed that incipient protein pathology in the medial temporal lobe instigates
the loss of episodic memory in Alzheimer's disease, one of the earliest cognitive deficits in …

Neural oscillations and brain stimulation in Alzheimer's disease

Z Jafari, BE Kolb, MH Mohajerani - Progress in neurobiology, 2020 - Elsevier
Aging is associated with alterations in cognitive processing and brain neurophysiology.
Whereas the primary symptom of amnestic mild cognitive impairment (aMCI) is memory …

Optimal deep brain stimulation sites and networks for stimulation of the fornix in Alzheimer's disease

AS Ríos, S Oxenford, C Neudorfer, K Butenko… - Nature …, 2022 - nature.com
Deep brain stimulation (DBS) to the fornix is an investigational treatment for patients with
mild Alzheimer's Disease. Outcomes from randomized clinical trials have shown that …

[HTML][HTML] Altered microRNA profiles in cerebrospinal fluid exosome in Parkinson disease and Alzheimer disease

YX Gui, H Liu, LS Zhang, W Lv, XY Hu - Oncotarget, 2015 - ncbi.nlm.nih.gov
The differential diagnosis of Parkinson's diseases (PD) is challenging, especially in the early
stages of the disease. We developed a microRNA profiling strategy for exosomal miRNAs …

Brain stimulation in Alzheimer's disease

CH Chang, HY Lane, CH Lin - Frontiers in psychiatry, 2018 - frontiersin.org
Brain stimulation techniques can modulate cognitive functions in many neuropsychiatric
diseases. Pilot studies have shown promising effects of brain stimulations on Alzheimer's …

Standard‐space atlas of the viscoelastic properties of the human brain

LV Hiscox, MDJ McGarry, H Schwarb… - Human brain …, 2020 - Wiley Online Library
Standard anatomical atlases are common in neuroimaging because they facilitate data
analyses and comparisons across subjects and studies. The purpose of this study was to …

Hippocampal pathology in amyotrophic lateral sclerosis: selective vulnerability of subfields and their associated projections

F Christidi, E Karavasilis, M Rentzos, G Velonakis… - Neurobiology of …, 2019 - Elsevier
Although hippocampal involvement in amyotrophic lateral sclerosis (ALS) has been
consistently highlighted by postmortem studies, memory impairment remains under …

Free water in white matter differentiates MCI and AD from control subjects

M Dumont, M Roy, PM Jodoin, FC Morency… - Frontiers in aging …, 2019 - frontiersin.org
Recent evidence shows that neuroinflammation plays a role in many neurological diseases
including mild cognitive impairment (MCI) and Alzheimer's disease (AD), and that free water …

Six months of piano training in healthy elderly stabilizes white matter microstructure in the fornix, compared to an active control group

K Jünemann, D Marie, F Worschech… - Frontiers in aging …, 2022 - frontiersin.org
While aging is characterized by neurodegeneration, musical training is associated with
experience-driven brain plasticity and protection against age-related cognitive decline …

[HTML][HTML] White matter microstructural abnormalities in amnestic mild cognitive impairment: A meta-analysis of whole-brain and ROI-based studies

J Yu, CLM Lam, TMC Lee - Neuroscience & Biobehavioral Reviews, 2017 - Elsevier
Studies that examined white matter (WM) alterations in amnestic mild cognitive impairment
(aMCI) abound. This timely meta-analysis aims to synthesize the results of these studies …