Current status and future prospective of vaccine development against Echinococcus granulosus

MM Pourseif, G Moghaddam, N Saeedi, A Barzegari… - Biologicals, 2018 - Elsevier
Cystic echinococcosis (CE) is one of the most important zoonotic parasite diseases in
human, livestock, and wildlife worldwide. Development of effective vaccines against CE …

Echinococcosis with particular reference to Southeast Asia

DP McManus - Advances in parasitology, 2010 - Elsevier
Echinococcosis is a zoonosis caused by adult or larval cestodes belonging to the genus
Echinococcus (family Taeniidae). The two major species of medical and public health …

The unique stem cell system of the immortal larva of the human parasite Echinococcus multilocularis

U Koziol, T Rauschendorfer, L Zanon Rodríguez… - Evodevo, 2014 - Springer
Background It is believed that in tapeworms a separate population of undifferentiated cells,
the germinative cells, is the only source of cell proliferation throughout the life cycle (similar …

Comparative analysis of Wnt expression identifies a highly conserved developmental transition in flatworms

U Koziol, F Jarero, PD Olson, K Brehm - BMC biology, 2016 - Springer
Background Early developmental patterns of flatworms are extremely diverse and difficult to
compare between distant groups. In parasitic flatworms, such as tapeworms, this is …

Heterologous expression of antigenic peptides in Bacillus subtilis biofilms

CM Vogt, EM Schraner, C Aguilar, C Eichwald - Microbial cell factories, 2016 - Springer
Background Numerous strategies have been developed for the display of heterologous
proteins in the surface of live bacterial carriers, which can be used as vaccines, immune …

Oral application of recombinant Bacillus subtilis spores to dogs results in a humoral response against specific Echinococcus granulosus paramyosin and tropomyosin …

CM Vogt, MT Armúa-Fernández, K Tobler… - Infection and …, 2018 - Am Soc Microbiol
Bacillus subtilis is known as an endospore-and biofilm-forming bacterium with probiotic
properties. We have recently developed a method for displaying heterologous proteins on …

Auto-induction for high yield expression of recombinant novel isoallergen tropomyosin from King prawn (Melicertus latisulcatus) for improved diagnostics and …

M Koeberl, SD Kamath, SR Saptarshi, MJ Smout… - Journal of …, 2014 - Elsevier
Food allergies are increasing worldwide, demonstrating a considerable public health
concern. Shellfish allergy is one of the major food groups causing allergic sensitization …

RNA sequencing reveals dynamic expression of genes related to innate immune responses in canine small intestinal epithelial cells induced by Echinococcus …

Z Wang, N Pu, W Zhao, X Chen, Y Zhang… - Frontiers in Veterinary …, 2024 - frontiersin.org
Background Dogs are definitive hosts of Echinococcus granulosus, with the small intestine
being the only site of parasitic infections. However, the immunomodulatory processes that …

Developmental expression of high molecular weight tropomyosin isoforms in Mesocestoides corti

U Koziol, A Costábile, MF Domínguez, A Iriarte… - Molecular and …, 2011 - Elsevier
Tropomyosins are a family of actin-binding proteins with diverse roles in actin filament
function. One of the best characterized roles is the regulation of muscle contraction …

Evaluation of protective immune responses induced by DNA vaccines encoding Echinococcus granulosus EgM123 protein in Beagle dogs

N Wang, J Xian, P Zhao, W Zhao, N Pu, X Jia… - Frontiers in Veterinary …, 2024 - frontiersin.org
Introduction Echinococcus granulosus, known as cystic echinococcosis, is a prominent
zoonotic parasitic disease of significant global concern. The definitive hosts serves as the …