The roles of vascular endothelial growth factor in bone repair and regeneration

K Hu, BR Olsen - Bone, 2016 - Elsevier
Vascular endothelial growth factor-A (VEGF) is one of the most important growth factors for
regulation of vascular development and angiogenesis. Since bone is a highly vascularized …

Arterial versus venous endothelial cells

NG Dela Paz, PA D'Amore - Cell and tissue research, 2009 - Springer
Vascular endothelial cells (ECs) form the inner lining of all blood vessels from the largest
artery and veins, viz., the aorta and venae cavae, respectively, to the capillaries that connect …

[PDF][PDF] Comprehensive physiology

DK Hamson, MM Roes, LAM Galea, R Terjung - 2016 - open.library.ubc.ca
Sex differences in neurological disease extend from incidence, severity, progression and
symptoms and may ultimately influence treatment. Cognitive disturbances are frequent in …

Influence of shear stress in perfusion bioreactor cultures for the development of three-dimensional bone tissue constructs: a review

RJ McCoy, FJ O'Brien - Tissue Engineering Part B: Reviews, 2010 - liebertpub.com
Bone tissue engineering aims to generate clinically applicable bone graft substitutes in an
effort to ease the demands and reduce the potential risks associated with traditional …

Mechanotransduction in osteogenesis

S Stewart, A Darwood, S Masouros… - Bone & joint …, 2020 - boneandjoint.org.uk
Bone is one of the most highly adaptive tissues in the body, possessing the capability to alter
its morphology and function in response to stimuli in its surrounding environment. The ability …

Role of shear-stress-induced VEGF expression in endothelial cell survival

NG Dela Paz, TE Walshe, LL Leach… - Journal of cell …, 2012 - journals.biologists.com
Vascular endothelial growth factor (VEGF) plays a crucial role in developmental and
pathological angiogenesis. Expression of VEGF in quiescent adult tissue suggests a …

Effect of intermittent shear stress on mechanotransductive signaling and osteoblastic differentiation of bone marrow stromal cells

MR Kreke, LA Sharp, Y Woo Lee… - … Engineering Part A, 2008 - liebertpub.com
Perfusion culture of osteoprogenitor cells seeded within porous scaffolds suitable for bone
tissue engineering is known to enhance deposition of a bone-like extracellular matrix, and …

VEGFA from early osteoblast lineage cells (Osterix+) is required in mice for fracture healing

EG Buettmann, JA McKenzie, N Migotsky… - Journal of Bone and …, 2019 - academic.oup.com
Bone formation via intramembranous and endochondral ossification is necessary for
successful healing after a wide range of bone injuries. The pleiotropic cytokine, vascular …

Cysteine-rich angiogenic inducer 61 (Cyr61): a novel soluble biomarker of acute myocardial injury improves risk stratification after acute coronary syndromes

R Klingenberg, S Aghlmandi, C Liebetrau… - European heart …, 2017 - academic.oup.com
Aims We aimed to identify a novel biomarker involved in the early events leading to an acute
coronary syndrome (ACS) and evaluate its role in diagnosis and risk stratification. Methods …

[PDF][PDF] Human mesenchymal stem cell responses to hydrostatic pressure and shear stress

P Becquart, M Cruel, T Hoc, L Sudre, K Pernelle… - Eur Cell …, 2016 - ecmjournal.org
The effects of mechanical stimuli to which cells are exposed in vivo are, at best, incompletely
understood; in this respect, gene-level information regarding cell functions which are …