Sjögren's syndrome (SS) is a chronic autoimmune disorder that is characterized by
dysfunction and destruction of the exocrine glands. Exocrinopathy is associated with …

Primary Sjögren's syndrome (pSS) is a chronic autoimmune disease characterized by
lymphocytic infiltration and tissue destruction of exocrine glands such as salivary glands …

Objective. To investigate functional properties of the germinal center (GC)–like structures
observed in salivary glands of patients with Sjögren's syndrome (SS) and to determine the …

Objective. There is no effective treatment for patients with primary Sjögren's syndrome (SS).
Since tumor necrosis factor (TNF) could be a key element in the pathogenesis of primary SS …

MATERIALS AND METHODS Materials Gly-Pro-4-methyl-coumaryl-7-amide (Gly-Pro-MCA)
was from Peptide Institute Inc.(Osaka, Japan). Sephacryl S-500 HR, Immobiline DryStrip gel …

MATERIALS AND METHODS Materials Gly-Pro-4-methyl-coumaryl-7-amide (Gly-Pro-MCA)
was purchased from Peptide Institute Inc.(Osaka, Japan). Sepharose CL-4B was purchased …

Objective. To test the hypothesis that the forma-tion of ectopic germinal center (GC)–like
structures in Sjögren's syndrome (SS) is associated with the ectopic expression of the …

Macrophage inflammatory protein-1 alpha (MIP-1α/CCL3) is a chemotactic chemokine
secreted by macrophages. It performs various biological functions, such as recruiting …

Objective. To elucidate the mechanism of the development of T cell infiltrates in the salivary
glands of patients with Sjögren's syndrome (SS), we studied T cell–attracting chemokines …

Investigating cytokines in tear fluid and saliva may offer valuable information for
understanding the pathogenesis of primary Sjögren's syndrome (pSS). Cytokine profiles in …