Post-traumatic osteoarthritis following ACL injury

LJ Wang, N Zeng, ZP Yan, JT Li, GX Ni - Arthritis research & therapy, 2020 - Springer
Post-traumatic osteoarthritis (PTOA) develops after joint injury. Specifically, patients with
anterior cruciate ligament (ACL) injury have a high risk of developing PTOA. In this review …

[HTML][HTML] Effects of exercise therapy on joint instability in patients with osteoarthritis of the knee: A systematic review

S Kawabata, K Murata, K Nakao, M Sonoo… - … and Cartilage Open, 2020 - Elsevier
Objective Abnormal load stress caused by joint instability has been reported to be one of the
factors responsible for the development of osteoarthritis (OA). However, few studies have …

Low-intensity pulsed ultrasound promotes autophagy-mediated migration of mesenchymal stem cells and cartilage repair

P Xia, X Wang, Q Wang, X Wang, Q Lin… - Cell …, 2021 - journals.sagepub.com
Mesenchymal stem cell (MSC) migration is promoted by low-intensity pulsed ultrasound
(LIPUS), but its mechanism is unclear. Since autophagy is known to regulate cell migration …

Platelet‐rich plasma combined with alendronate reduces pain and inflammation in induced osteoarthritis in rats by inhibiting the nuclear Factor‐Kappa B signaling …

F Xin, H Wang, F Yuan, Y Ding - BioMed Research International, 2020 - Wiley Online Library
Purpose. Osteoarthritis (OA) is one of the common degenerative diseases of the joint in the
world. This study was designed to explore the effect of platelet‐rich plasma (PRP) combined …

[HTML][HTML] The difference in joint instability affects the onset of cartilage degeneration or subchondral bone changes

K Arakawa, K Takahata, S Enomoto, Y Oka… - Osteoarthritis and …, 2022 - Elsevier
Objective It has been debated whether the onset of knee osteoarthritis is initiated in cartilage
or subchondral bone. The purpose of this study was to clarify the effects of increasing or …

Retracted: Long noncoding RNA MALAT1 alleviates lipopolysaccharide‐induced inflammatory injury by upregulating microRNA‐19b in murine chondrogenic ATDC5 …

L Pan, D Liu, L Zhao, L Wang, M Xin, X Li - 2018 - Wiley Online Library
Osteoarthritis is the most frequent chronic bone‐joint disease in middle‐aged and older
people worldwide. This study investigated the effects of long noncoding RNA metastasis …

Association between oncostatin M expression and inflammatory phenotype in experimental arthritis models and osteoarthritis patients

JP Garcia, L Utomo, I Rudnik-Jansen, J Du… - Cells, 2021 - mdpi.com
Pro-inflammatory cytokines are considered to play a major role in osteoarthritis (OA), yet so
far, the specific cytokines involved in the pathology of OA have not been identified …

[HTML][HTML] Involvement of TLR4 in the protective effect of intra-articular administration of curcumin on rat experimental osteoarthritis

D Yan, B He, J Guo, S Li, J Wang - Acta Cirurgica Brasileira, 2019 - SciELO Brasil
Purpose In view of the principal role of Toll-like receptor 4 (TLR4) in mediating sterile
inflammatory response contributing to osteoarthritis (OA) pathogenesis, we used …

Alpha-2-macroglobulin attenuates posttraumatic osteoarthritis cartilage damage by inhibiting inflammatory pathways with modified intra-articular drilling in a Yucatan …

C Sun, K Chang, BC Fleming… - … American Journal of …, 2024 - journals.sagepub.com
Background: Posttraumatic osteoarthritis (PTOA) arises secondarily to joint trauma and is
driven by catabolic inflammatory pathways. Alpha-2-macroglobulin (α2M) is a naturally …

Hesperetin exhibits anti-inflammatory effects on chondrocytes via the AMPK pathway to attenuate anterior cruciate ligament transection-induced osteoarthritis

J Wu, Y Qian, C Chen, F Feng, L Pan, L Yang… - Frontiers in …, 2021 - frontiersin.org
This study aimed to determine whether hesperetin (HPT) has chondroprotective effects
against the TNF-α-induced inflammatory response of chondrocytes and related mechanisms …