The keloid disorder: heterogeneity, histopathology, mechanisms and models

GC Limandjaja, FB Niessen, RJ Scheper… - Frontiers in cell and …, 2020 - frontiersin.org
Keloids constitute an abnormal fibroproliferative wound healing response in which raised
scar tissue grows excessively and invasively beyond the original wound borders. This …

Histology and vascular architecture study of keloid tissue to outline the possible terminology of keloid skin flaps

Y Teng, Y Hao, H Liu, M Shan, Q Chen, K Song… - Aesthetic Plastic …, 2022 - Springer
Background Using the keloid “epidermis” to cover a wound is widely used during treatment
for keloids. Many flap terminologies have been used in literature. However, the definition of …

Complete excision of proliferating core in auricular keloids significantly reduces local recurrence: A prospective study

Y Chong, CW Kim, YS Kim, CH Chang… - The Journal of …, 2018 - Wiley Online Library
Keloids are mysterious soft‐tissue tumors that are characterized by excessive reparative
processes composed of collagen‐forming fibroblasts and inflammatory cells. Generally …

Circular RNA hsa_circ_0043688 serves as a competing endogenous RNA for microRNA‐145‐5p to promote the progression of Keloids via Fibroblast growth factor‐2

Y Liu, X Wang, Z Ni, Y Li, J Song… - Journal of Clinical …, 2022 - Wiley Online Library
Background Keloids are benign fibroproliferative skin tumors. Circular RNA (circRNA)
hsa_circ_0043688 has been exhibited to the freakishly expressed in keloid tissues. Here …

Intralesional excision as a surgical strategy to manage keloid scars: what's the evidence?

I Goutos - Scars, Burns & Healing, 2019 - journals.sagepub.com
Introduction: Keloid scars are a particularly challenging clinical entity and a variety of
management approaches have been described in the literature including intralesional …

Tissue RNA sequencing reveals novel biomarkers associated with postoperative keloid recurrence

Y Tang, K Ren, X Yin, Y Yang, F Fang, B Zhou… - Journal of Clinical …, 2023 - mdpi.com
Keloids can be resected through surgery, but they may still recur. The purpose of this study
was to explore the biomarkers to predict the postoperative recurrence of keloids. Patients …

miR-21 promotes collagen production in keloid via Smad7

R Zhou, C Wang, C Wen, D Wang - Burns, 2017 - Elsevier
Objective To explore the biological function of miR-21 in the formation of keloid. Methods
Normal skin and keloid tissue samples underwent histopathologic study and qPCR analysis …

Successful eradication of helical rim keloids with surgical excision followed by pressure therapy using a combination of magnets and silicone gel sheeting

TH Park, DK Rah - International wound journal, 2017 - Wiley Online Library
Extremely limited data are available for the treatment of helical rim keloids. The purpose of
the present study was to demonstrate the successful treatment of helical rim keloids using …

Histological analysis of hyalinised keloidal collagen formation in earlobe keloids over time: collagen hyalinisation starts in the perivascular area

NM Matsumoto, WX Peng, M Aoki… - International Wound …, 2017 - Wiley Online Library
Keloids grow and do not regress. They are characterised histologically by hyalinised
keloidal collagen (HKC). HKC amounts vary, and the mechanism by which they form is …

[引用][C] Functional histopathology of keloid disease

N Jumper, R Paus, A Bayat - 2015 - F. Hernández y Juan F. Madrid …