A biological definition of neuronal α-synuclein disease: towards an integrated staging system for research

T Simuni, LM Chahine, K Poston, M Brumm… - The Lancet …, 2024 - thelancet.com
Parkinson's disease and dementia with Lewy bodies are currently defined by their clinical
features, with α-synuclein pathology as the gold standard to establish the definitive …

[HTML][HTML] NIA-AA research framework: toward a biological definition of Alzheimer's disease

CR Jack Jr, DA Bennett, K Blennow, MC Carrillo… - Alzheimer's & …, 2018 - Elsevier
Abstract In 2011, the National Institute on Aging and Alzheimer's Association created
separate diagnostic recommendations for the preclinical, mild cognitive impairment, and …

EANM procedure guidelines for brain PET imaging using [18F]FDG, version 3

E Guedj, A Varrone, R Boellaard, NL Albert… - European journal of …, 2022 - Springer
The present procedural guidelines summarize the current views of the EANM Neuro-
Imaging Committee (NIC). The purpose of these guidelines is to assist nuclear medicine …

Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium

IG McKeith, BF Boeve, DW Dickson, G Halliday… - Neurology, 2017 - AAN Enterprises
The Dementia with Lewy Bodies (DLB) Consortium has refined its recommendations about
the clinical and pathologic diagnosis of DLB, updating the previous report, which has been …

Dementia prevention, intervention, and care

G Livingston, A Sommerlad, V Orgeta, SG Costafreda… - The lancet, 2017 - thelancet.com
Executive summary Acting now on dementia prevention, intervention, and care will vastly
improve living and dying for individuals with dementia and their families, and in doing so …

Clinical neurology and epidemiology of the major neurodegenerative diseases

MG Erkkinen, MO Kim… - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
Neurodegenerative diseases are a common cause of morbidity and cognitive impairment in
older adults. Most clinicians who care for the elderly are not trained to diagnose these …

Mental health care for older adults: recent advances and new directions in clinical practice and research

CF Reynolds 3rd, DV Jeste, PS Sachdev… - World …, 2022 - Wiley Online Library
The world's population is aging, bringing about an ever‐greater burden of mental disorders
in older adults. Given multimorbidities, the mental health care of these people and their …

Brain-first versus gut-first Parkinson's disease: a hypothesis

P Borghammer… - Journal of Parkinson's …, 2019 - content.iospress.com
Parkinson's disease (PD) is a highly heterogeneous disorder, which probably consists of
multiple subtypes. Aggregation of misfolded alpha-synuclein and propagation of these …

Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria

B Dubois, HH Feldman, C Jacova, H Hampel… - The Lancet …, 2014 - thelancet.com
In the past 8 years, both the International Working Group (IWG) and the US National Institute
on Aging–Alzheimer's Association have contributed criteria for the diagnosis of Alzheimer's …

The α-synuclein origin and connectome model (SOC Model) of Parkinson's disease: explaining motor asymmetry, non-motor phenotypes, and cognitive decline

P Borghammer - Journal of Parkinson's disease, 2021 - content.iospress.com
A new model of Parkinson's disease (PD) pathogenesis is proposed, the α-Synuclein Origin
site and Connectome (SOC) model, incorporating two aspects of α-synuclein pathobiology …