Developmental origins of metabolic diseases

DJ Hoffman, TL Powell, ES Barrett… - Physiological …, 2021 - journals.physiology.org
Almost 2 billion adults in the world are overweight, and more than half of them are classified
as obese, while nearly one-third of children globally experience poor growth and …

Diabetes during pregnancy: a maternal disease complicating the course of pregnancy with long-term deleterious effects on the offspring. a clinical review

A Ornoy, M Becker, L Weinstein-Fudim… - International Journal of …, 2021 - mdpi.com
In spite of the huge progress in the treatment of diabetes mellitus, we are still in the situation
that both pregestational (PGDM) and gestational diabetes (GDM) impose an additional risk …

Maternal-fetal cross-talk via the placenta: influence on offspring development and metabolism

AC Kramer, T Jansson, TL Bale, TL Powell - Development, 2023 - journals.biologists.com
Compelling epidemiological and animal experimental data demonstrate that
cardiometabolic and neuropsychiatric diseases originate in a suboptimal intrauterine …

Expression of nutrient transporters in placentas affected by gestational diabetes: role of leptin

P Guadix, I Corrales, T Vilariño-García… - Frontiers in …, 2023 - frontiersin.org
Gestational diabetes mellitus (GDM) is the most frequent pathophysiological state of
pregnancy, which in many cases produces fetuses with macrosomia, requiring increased …

Fetomaternal expression of glucose transporters (GLUTs)—biochemical, cellular and clinical aspects

R Sibiak, K Ozegowska, E Wender-Ozegowska… - Nutrients, 2022 - mdpi.com
Several types of specialized glucose transporters (GLUTs) provide constant glucose
transport from the maternal circulation to the developing fetus through the placental barrier …

Differential expression of glucose transporter proteins GLUT-1, GLUT-3, GLUT-8 and GLUT-12 in the placenta of macrosomic, small-for-gestational-age and growth …

PJ Stanirowski, D Szukiewicz, A Majewska… - Journal of Clinical …, 2021 - mdpi.com
Placental transfer of glucose constitutes one of the major determinants of the intrauterine
foetal growth. The objective of the present study was to evaluate the expression of glucose …

Role of placental glucose transporters in determining fetal growth

NP Joshi, AR Mane, AS Sahay, DP Sundrani… - Reproductive …, 2021 - Springer
Maternal nutrient availability and its transport through the placenta are crucial for fetal
development. Nutrients are transported to the fetus via specific transporters present on the …

Placental expression of glucose transporters GLUT‐1, GLUT‐3, GLUT‐8 and GLUT‐12 in pregnancies complicated by gestational and type 1 diabetes mellitus

PJ Stanirowski, D Szukiewicz… - Journal of Diabetes …, 2022 - Wiley Online Library
ABSTRACT Aims/Introduction The aim of the present study was to evaluate the placental
expression of glucose transporters GLUT‐1, GLUT‐3, GLUT‐8 and GLUT‐12 in term …

Support provided by caregivers for community-dwelling obesity individuals: focus on elderly and Hispanics

T Basu, U Sehar, A Selman, AP Reddy, PH Reddy - Healthcare, 2023 - mdpi.com
Obesity is a chronic disease marked by the buildup of extra adipose tissue and a higher
chance of developing concomitant illnesses such as heart disease, diabetes, high blood …

Role of melatonin receptor 1B gene polymorphism and its effect on the regulation of glucose transport in gestational diabetes mellitus

L Wei, Y Jiang, P Gao, J Zhang, X Zhou, S Zhu… - Journal of Zhejiang …, 2023 - Springer
Abstract Melatonin receptor 1B (MT2, encoded by the MTNR1B gene), a high-affinity
receptor for melatonin, is associated with glucose homeostasis including glucose uptake …