Advances in the application of extracellular vesicles derived from three-dimensional culture of stem cells

W Chen, P Wu, C Jin, Y Chen, C Li, H Qian - Journal of …, 2024 - Springer
Stem cells (SCs) have been used therapeutically for decades, yet their applications are
limited by factors such as the risk of immune rejection and potential tumorigenicity …

Oligodendrocytes in human induced pluripotent stem cell-derived cortical grafts remyelinate adult rat and human cortical neurons

R Martinez-Curiel, L Jansson, O Tsupykov, N Avaliani… - Stem Cell Reports, 2023 - cell.com
Neuronal loss and axonal demyelination underlie long-term functional impairments in
patients affected by brain disorders such as ischemic stroke. Stem cell-based approaches …

Production of Human Neurogenin 2-Inducible Neurons in a Three-Dimensional Suspension Bioreactor

J Wihan, I Karnatz, I Sébastien, R Kettenhofen… - JoVE (Journal of …, 2023 - jove.com
The derivation of neuronal lineage cells from human induced pluripotent stem cells (hiPSCs)
marked a milestone in brain research. Since their first advent, protocols have been …

Hemodynamic forces regulate cardiac regeneration-responsive enhancer activity during ventricle regeneration

F Geng, J Ma, X Li, Z Hu, R Zhang - International journal of molecular …, 2021 - mdpi.com
Cardiac regenerative capacity varies widely among vertebrates. Zebrafish can robustly
regenerate injured hearts and are excellent models to study the mechanisms of heart …

Hydrogel encapsulated stem cells facilitate successful repair after spinal cord injury in rats and monkeys

T Li, P Li, H Yuan, X Zhu, L Xiong, S Zhao, J Li, T Chen… - 2023 - researchsquare.com
Promoting axonal regeneration to form nascent circuits after spinal cord injury (SCI) is a
considerable challenge. While cell-based transplantation is considered a top candidate for …

Oligodendrocytes in human iPS cell-derived cortical grafts remyelinate adult rat and human cortical neurons

R Martinez-Curiel, L Jansson, O Tsupykov, N Avaliani… - bioRxiv, 2023 - biorxiv.org
Neuronal loss and axonal demyelination underlie long-term functional impairments in
patients affected by brain disorders such as ischemic stroke. Stem cell-based approaches …