TorsinA is essential for neuronal nuclear pore complex localization and maturation
As lifelong interphase cells, neurons face an array of unique challenges. A key challenge is
regulating nuclear pore complex (NPC) biogenesis and localization, the mechanisms of …
regulating nuclear pore complex (NPC) biogenesis and localization, the mechanisms of …
[HTML][HTML] TorsinA is essential for the timing and localization of neuronal nuclear pore complex biogenesis
Nuclear pore complexes (NPCs) regulate information transfer between the nucleus and
cytoplasm. NPC defects are linked to several neurological diseases, but the processes …
cytoplasm. NPC defects are linked to several neurological diseases, but the processes …
Striatal cholinergic interneuron development in models of DYT1 dystonia
LN Miterko-Myers - Dystonia, 2024 - frontierspartnerships.org
Dystonia is a neurodevelopmental disorder characterized by severe involuntary twisting
movements, hypothesized to arise from a dysfunctional motor network involving the cortex …
movements, hypothesized to arise from a dysfunctional motor network involving the cortex …
Leveraging explainable deep learning methodologies to elucidate the biological underpinnings of Huntington's disease using single-cell RNA sequencing data
S Gao, Y Wang, J Wang, Y Dong - BMC genomics, 2024 - Springer
Background Huntington's disease (HD) is a hereditary neurological disorder caused by
mutations in HTT, leading to neuronal degeneration. Traditionally, HD is associated with the …
mutations in HTT, leading to neuronal degeneration. Traditionally, HD is associated with the …