Trauma, adversity, and biological aging: behavioral mechanisms relevant to treatment and theory

KJ Bourassa, DA Sbarra - Translational Psychiatry, 2024 - nature.com
Although stress and adversity are largely universal experiences, people exposed to greater
hardship are at increased risk for negative health consequences. Recent studies identify …

Immunophenotypes in psychosis: is it a premature inflamm-aging disorder?

S Chen, Y Tan, L Tian - Molecular Psychiatry, 2024 - nature.com
Immunopsychiatric field has rapidly accumulated evidence demonstrating the involvement of
both innate and adaptive immune components in psychotic disorders such as …

Maternal adverse childhood experiences (ACEs) and DNA methylation of newborns in cord blood

P Collender, AK Bozack, S Veazie… - Clinical …, 2023 - Springer
Abstract Background Adverse childhood experiences (ACEs) increase the risk of poor health
outcomes later in life. Psychosocial stressors may also have intergenerational health effects …

DNA methylation at birth and lateral ventricular volume in childhood: a neuroimaging epigenetics study

M Luo, E Walton, A Neumann, CHL Thio… - Journal of Child …, 2024 - Wiley Online Library
Background Lateral ventricular volume (LVV) enlargement has been repeatedly linked to
schizophrenia; yet, what biological factors shape LVV during early development remain …

Placental transcriptomic signatures of prenatal and preconceptional maternal stress

BH Baker, S Freije, JW MacDonald, TK Bammler… - Molecular …, 2024 - nature.com
Prenatal exposure to maternal psychological stress is associated with increased risk for
adverse birth and child health outcomes. Accumulating evidence suggests that …

Genome-wide neonatal epigenetic changes associated with maternal exposure to the COVID-19 pandemic

K Kocher, S Bhattacharya… - BMC medical …, 2023 - Springer
Background During gestation, stressors to the fetus, including viral exposure or maternal
psychological distress, can fundamentally alter the neonatal epigenome, and may be …

Prenatal exposure to genocide and subsequent adverse childhood events are associated with DNA methylation of SLC6A4, BDNF, and PRDM8 in early adulthood …

LM Rivera, G Uwizeye, H Stolrow, B Christensen… - Scientific Reports, 2024 - nature.com
We investigated associations between prenatal genocidal trauma, including maternal rape,
and postnatal adverse childhood experiences (ACEs) on DNA methylation of genes …

Early exposure to maternal stress and risk for atopic dermatitis in children: A systematic review and meta‐analysis

Y Ai, J Huang, TT Zhu - Clinical and Translational Allergy, 2024 - Wiley Online Library
Background The incidence of atopic dermatitis (AD) in children is increasing. Early exposure
to stress factors may be associated with the AD development. This study aimed to …

DNA methylation as a possible causal mechanism linking childhood adversity and health: Results from two-sample mendelian randomization study

IK Schuurmans, EC Dunn… - American Journal of …, 2024 - academic.oup.com
Childhood adversity is an important risk factor for adverse health across the life course.
Epigenetic modifications, such as DNA methylation (DNAm), are one hypothesized …

Mediation of DNA methylation (cg04622888 and cg05037505) in the association between childhood maltreatment and non-suicidal self-injury in early adolescents

Y Li, S Guo, X Xie, Y Zhang, T Jiao, Y Wu, Y Ma… - European Child & …, 2024 - Springer
It is unclear whether DNA methylation underlies the association between childhood
maltreatment (CM) and non-suicidal self-injury (NSSI) in early adolescents. We aim to …