Krüppel‐like factor 5 (KLF5) is a member of the KLF family. Recent studies have suggested
that KLF5 regulates the expression of a large number of new target genes and participates …

The urothelium is a stratified epithelium composed of basal cells, one or more layers of
intermediate cells, and an upper layer of differentiated umbrella cells. Most bladder cancers …

Immune microenvironment plays a critical role in lung cancer control versus progression and
metastasis. In this investigation, we explored the effect of tumor-infiltrating lymphocyte …

Accumulating evidences indicate that long noncoding RNAs (lncRNAs) and circular RNAs
(circRNAs) play important roles in tumorigenesis. However, the mechanisms remain largely …

The mechanisms underlying the role of CXCL5 in tumor angiogenesis have not been fully
defined. Here, we examined the effect of CXCL5 on tumor angiogenesis in colorectal cancer …

Cervical cancer (CC) is the fourth leading cause of deaths in gynecological malignancies.
Although the etiology of CC has been extensively investigated, the exact pathogenesis of …

The Krüppel-like family of transcription factors plays critical roles in human development and
is associated with cancer pathogenesis. Krüppel-like factor 5 gene (KLF5) has been shown …

Glioblastoma (GBM) is the most aggressive and malignant primary tumor. Angiogenesis
plays a critical role in the progression of GBM. Previous studies have indicated that long non …

Background Hypoxia-mediated chemoresistance has been regarded as an important
obstacle in the development of cancer treatment. Knockdown of krüppel-like factor 5 (KLF5) …

Previous studies have reported that microRNAs regulate gene expression and transcription.
miR-21 have been identified to play a role in many types of cancer. KLF5 functions as a …