Neurexins and neuroligins are emerging as central organizing molecules for excitatory
glutamatergic and inhibitory GABAergic synapses in mammalian brain. They function as cell …

Membrane-associated guanylate kinases (MAGUKs) are a family of scaffold proteins that are
highly enriched in synapses and are responsible for organizing the numerous protein …

Cell adhesion represents the most direct way of coordinating synaptic connectivity in the
brain. Recent evidence highlights the importance of a trans-synaptic interaction between …

A fundamental physical interaction exists across the synapse. It is mediated by synaptic
adhesion molecules, and is among the earliest and most indispensable of molecular events …

Neuroligins are postsynaptic cell-adhesion molecules that bind presynaptic neurexins and
are genetically linked to autism. Neuroligins are proposed to organize synaptogenesis …

Excitability of individual neurons dictates the overall excitation in specifi c brain circuits. This
process is thought to be regulated by molecules that regulate synapse number, morphology …

The mechanisms governing the recruitment of functional glutamate receptors at nascent
excitatory postsynapses following initial axon-dendrite contact remain unclear. We …

Neuroligins are postsynaptic cell adhesion molecules that are relevant to many
neurodevelopmental disorders. They are differentially enriched at the postsynapse and …

Synaptic adhesion molecules are known to participate in various steps of synapse
development including initial contacts between dendrites and axons, formation of early …

Cell adhesion molecules are key players in transsynaptic communication, precisely
coordinating presynaptic differentiation with postsynaptic specialization. At glutamatergic …