Temperature dependence of haemoglobin–oxygen affinity in heterothermic vertebrates: mechanisms and biological significance

RE Weber, KL Campbell - Acta Physiologica, 2011 - Wiley Online Library
Abstract As demonstrated by August Krogh et al. a century ago, the oxygen‐binding reaction
of vertebrate haemoglobin is cooperative (described by sigmoid O2 equilibrium curves) and …

Regulation of blood oxygen transport in hibernating mammals

IG Revsbech, A Fago - Journal of Comparative Physiology B, 2017 - Springer
Along with the periodic reductions in O 2 requirements of mammalian hibernators during
winter, the O 2 affinity of the blood of mammalian hibernators is seasonally regulated to help …

ATP-induced temperature independence of hemoglobin–O2 affinity in heterothermic billfish

RE Weber, KL Campbell, A Fago… - Journal of …, 2010 - journals.biologists.com
The inverse relationship between temperature and hemoglobin–O2 affinity resulting from the
exothermic nature of heme oxygenation favors O2 unloading from blood to warm …

Enthalpic partitioning of the reduced temperature sensitivity of O2 binding in bovine hemoglobin

RE Weber, A Fago, KL Campbell - … and Physiology Part A: Molecular & …, 2014 - Elsevier
The oxygenation enthalpy of the heme groups of hemoglobin (Hb) is inherently exothermic,
resulting in decreased Hb-O 2 affinity with rising temperature. However, oxygenation is …

From the arctic to fetal life: physiological importance and structural basis of an additional chloride-binding site in haemoglobin

MC De Rosa, M Castagnola, C Bertonati… - Biochemical …, 2004 - portlandpress.com
Haemoglobins from mammals of sub-Arctic and Arctic species, as well as fetal human Hb,
are all characterized by a significantly lower Δ H of oxygenation compared with the majority …

Decrease in the red cell cofactor 2,3-diphosphoglycerate increases hemoglobin oxygen affinity in the hibernating brown bear Ursus arctos

IG Revsbech, H Malte, O Fröbert… - American Journal …, 2013 - journals.physiology.org
During winter hibernation, brown bears (Ursus arctos) reduce basal O2 consumption rate
to∼ 25% compared with the active state, while body temperature decreases moderately …

Enthalpic consequences of reduced chloride binding in Andean frog (Telmatobius peruvianus) hemoglobin

RE Weber - Journal of Comparative Physiology B, 2014 - Springer
Based on the exothermic nature of heme oxygenation, the O 2 affinity of hemoglobin (Hb)
decreases with increasing temperature, which may be physiologically advantageous in …

Kunnskapsstatus og kunnskapsbehov for forvaltning av rovvilt i Norge

JDC Linnell, T Tveraa, I Hansen, H Andrén, J Persson… - 2015 - brage.nina.no
Miljødirektoratet har bestilt denne rapporten for å identifisere kunnskapshull vedrørende
rovvilt (gaupe, brunbjørn, ulv, jerv og kongeørn) i Skandinavia, med særlig fokus på …

[图书][B] Hemoglobin function in vertebrates: molecular adaptation in extreme and temperate environments

G Di Prisco, B Giardina, RE Weber - 2000 - books.google.com
The annual Congress of the Italian Biochemical and Molecular Biology Society (SIB) was
held in September 1999 in Alghero, Sardegna, Italy. The programme envisaged a …

Functional characterisation of Eskimo dog Hemoglobin: I. Interaction of Cl− and 2, 3-DPG and its importance to oxygen unloading at low temperature

AJ Bårdgard, I Strand, M Nuutinen, E Jul… - … and Physiology Part A …, 1997 - Elsevier
The oxygen binding properties of hemoglobin and some hematological parameters in
Eskimo dogs (belonging to Canis lupus familiaris) in Ilulissat/Jacobshavn, Greenland were …