Natural variants of crops are generated from wild progenitor plants under both natural and
human selection. Diverse crops that are able to adapt to various environmental conditions …

The rapid expansion of next‐generation sequencing has yielded a powerful array of tools to
address fundamental biological questions at a scale that was inconceivable just a few years …

This paper describes a new program SnpSift for filtering differential DNA sequence variants
between two or more experimental genomes after genotoxic chemical exposure. Here, we …

We present a new approach to genotyping based on multiplexed shotgun sequencing that
can identify recombination breakpoints in a large number of individuals simultaneously at a …

Research in the fruit fly Drosophila melanogaster has led to insights in neural development,
axon guidance, ion channel function, synaptic transmission, learning and memory, diurnal …

The long-lasting success of forward genetic screens relies on the simple molecular basis of
the characterized phenotypes, which are typically caused by mutations in single genes …

Museum specimens include genetic information from when they were collected. This
historical information, which is very difficult to ascertain from samples collected currently …

Targeted quantification of DNA methylation allows for interrogation of the most informative
loci across many samples quickly and cost-effectively. Here we report improved bisulfite …

Background Gene-targeted and genome-wide markers are crucial to advance evolutionary
biology, agriculture, and biodiversity conservation by improving our understanding of …

Background Triticum monococcum L., an A genome diploid einkorn wheat, was the first
domesticated crop. As a diploid, it is attractive genetic model for the study of gene structure …