Peptide-based vaccines for tuberculosis

W Gong, C Pan, P Cheng, J Wang, G Zhao… - Frontiers in …, 2022 - frontiersin.org
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. As a
result of the coronavirus disease 2019 (COVID-19) pandemic, the global TB mortality rate in …

Host–pathogen interaction in leishmaniasis: immune response and vaccination strategies

H Yasmin, A Adhikary, MN Al-Ahdal, S Roy, U Kishore - Immuno, 2022 - mdpi.com
Leishmaniasis is a zoonotic and vector-borne infectious disease that is caused by the genus
Leishmania belonging to the trypanosomatid family. The protozoan parasite has a digenetic …

Integrated core proteomics, subtractive proteomics, and immunoinformatics investigation to unveil a potential multi-epitope vaccine against schistosomiasis

A Rehman, S Ahmad, F Shahid, A Albutti… - Vaccines, 2021 - mdpi.com
Schistosomiasis is a parasitic infection that causes considerable morbidity and mortality in
the world. Infections of parasitic blood flukes, known as schistosomes, cause the disease …

Immunoinformatics Approach to Design a Multi-Epitope Nanovaccine against Leishmania Parasite: Elicitation of Cellular Immune Responses

M Margaroni, M Agallou, E Tsanaktsidou, O Kammona… - Vaccines, 2023 - mdpi.com
Leishmaniasis is a vector-borne disease caused by an intracellular parasite of the genus
Leishmania with different clinical manifestations that affect millions of people worldwide …

Engineering and design of promising T-cell-based multi-epitope vaccine candidates against leishmaniasis

ER Basmenj, M Arastonejad, M Mamizadeh, M Alem… - Scientific Reports, 2023 - nature.com
Cutaneous leishmaniasis (CL) is a very common parasitic infection in subtropical areas
worldwide. Throughout decades, there have been challenges in vaccine design and …

Insights into the drug screening approaches in leishmaniasis

B Gopu, P Kour, R Pandian, K Singh - International Immunopharmacology, 2023 - Elsevier
Leishmaniasis, a tropically neglected disease, is responsible for the high mortality and
morbidity ratio in poverty-stricken areas. Currently, no vaccine is available for the complete …

In-silico design of an immunoinformatics based multi-epitope vaccine against Leishmania donovani

S Saha, S Vashishtha, B Kundu, M Ghosh - BMC bioinformatics, 2022 - Springer
Abstract Background Visceral Leishmaniasis (VL) is a fatal vector-borne parasitic disorder
occurring mainly in tropical and subtropical regions. VL falls under the category of neglected …

A multi-epitope vaccine GILE against Echinococcus Multilocularis infection in mice

P Zhou, Z Zhou, M Huayu, L Wang, L Feng… - Frontiers in …, 2023 - frontiersin.org
Introduction The objective of this study is to construct a multi-epitope vaccine GILE
containing B-cell and T-cell epitopes against Echinococcus Multilocularis (E. multilocularis) …

Unveiling the multifaceted role of toll-like receptors in immunity of aquatic animals: pioneering strategies for disease management

MU Ghani, J Chen, Z Khosravi, Q Wu, Y Liu… - Frontiers in …, 2024 - frontiersin.org
The pattern recognition receptor (PRR), which drives innate immunity, shields the host
against invasive pathogens. Fish and other aquatic species with poorly developed adaptive …

A comprehensive review on the dynamic role of toll-like receptors (TLRs) in frontier aquaculture research and as a promising avenue for fish disease management

S Mahapatra, B Ganguly, S Pani, A Saha… - International Journal of …, 2023 - Elsevier
Toll-like receptors (TLRs) represent a conserved group of germline-encoded pattern
recognition receptors (PRRs) that recognize pathogen-associated molecular patterns …