Human-associated bacteria secrete modified peptides to control host physiology and
remodel the microbiota species composition. Here we scanned 2,229 Human Microbiome …

Radical SAM enzymes involved in the biosynthesis of ribosomally synthesized and post-
translationally modified peptides catalyze unusual transformations that lead to unique …

Advances in genome sequencing and bioinformatics methods have identified a myriad of
biosynthetic gene clusters (BGCs) encoding uncharacterized molecules. By mining …

Ribosomally synthesized and post-translationally modified peptides (RiPPs) represent a
significant potential for novel therapeutic applications because of their bioactive properties …

Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a major
class of natural products with diverse chemical structures and potent biological activities. A …

Ribosomally synthesized lanthionine-containing peptides (lanthipeptides) have emerged as
a promising source of antimicrobials against multidrug resistance pathogens. An effective …

Advances in genome sequencing and bioinformatics methods have identified myriad
biosynthetic gene clusters (BGCs) encoding uncharacterized molecules. By examining …

Background Lanthipeptides are a rapidly expanding family of ribosomally synthesized and
post-translationally modified natural compounds with diverse biological functions …

Natural products and their derivatives account for the majority of approved drugs. New
antibiotics are urgently needed to combat increasing antibiotic resistance and fatalities …