One-pot synthesis of substituted amides from nitriles under mild reaction conditions in aqueous surfactant TPGS-750-M

M Parmentier, P Palamini, B Gosselin, M Jakobi… - Catalysis today, 2024 - Elsevier
A copper-catalyzed amide bond synthesis is described under micellar aqueous reaction
conditions with THF as co-solvent. By using commercially available copper iodide catalyst …

Investigating the underappreciated hydrolytic instability of 1, 8-diazabicyclo [5.4. 0] undec-7-ene and related unsaturated nitrogenous bases

AM Hyde, R Calabria, R Arvary, X Wang… - … Process Research & …, 2019 - ACS Publications
The widespread use of amidine and guanidine bases in synthetic chemistry merits a
thorough understanding of their chemical properties. The propensity of these reagents to …

Fe3O4@SiO2@KIT-6@2-ATP@CuI as a catalyst for hydration of benzonitriles and reduction of nitroarenes

Z Moradi, A Ghorbani-Choghamarani - Scientific Reports, 2023 - nature.com
In this paper, a new type of magnetic mesoporous material (Fe3O4@ SiO2@ KIT-6@ 2-
ATP@ CuI) was designed and synthesized and its application in the synthesis of amides …

Cesium Carbonate (Cs2CO3) in Organic Synthesis: A Sexennial Update (2018 to Date)

R Varala, KMM Achari, M Hussein… - Current Organic …, 2025 - benthamdirect.com
Cesium carbonate is an alkali carbonate salt that has numerous applications and has been
proven to be a mild inorganic base in organic synthesis. It has garnered significant attention …

Mild Palladium‐Catalyzed Cyanation of Unprotected 2‐Iodoglycals in Aqueous Media as Versatile Tool to Access Diverse C2‐Glycoanalogues

M Malinowski, T Van Tran… - Advanced Synthesis …, 2020 - Wiley Online Library
Access to unprotected 2‐cyano‐glycals via a mild palladium‐catalyzed cyanation of
protecting groups‐free 2‐iodoglycals in aqueous media has been developed. Diverse glycal …

Visible Light-Induced Divergent Deoxygenation/Hydroxymethylation of Pyridine N-Oxides

C Feng, H Guo, A Ding - The Journal of Organic Chemistry, 2025 - ACS Publications
This study explores the deoxygenation of pyridine N-oxides and presents a one-step
photoredox method for the direct synthesis of 2-hydroxymethylated pyridines from pyridine N …

Direct access to carbamates via acylation of arylamines with dialkyl azodicarboxylates under metal-free conditions

L Fan, M He, X Liu, F He, L Wu, G Yang… - Organic & …, 2023 - pubs.rsc.org
A novel C–N coupling of various arylamines with dialkyl azodicarboxylates under metal-free
conditions for the rapid assembly of carbamates has been achieved. This established …

Easy and efficient direct conversion of aryl nitrile into aryl amide

S Kumar, R Ambatwar, GL Khatik - Research on Chemical Intermediates, 2023 - Springer
Aryl amides and amide derivatives are important functionality in drug and drug discovery, as
many drugs have it as an integral part. However, the synthesis of amide requires the …

Trash to treasure: eco-friendly and practical synthesis of amides by nitriles hydrolysis in WEPPA

Y Sun, W Jin, C Liu - Molecules, 2019 - mdpi.com
The hydration of nitriles to amides in a water extract of pomelo peel ash (WEPPA) was
realized with moderate to excellent yields without using external transition metals, bases or …

Complex‐mediated nucleophilic aromatic substitution with aryl nitriles to realize intramolecular flapping‐restricted D‐A AIEgens for bioimaging

F Liu, J Liu, J Gong, R Lin, S Qiu, Z Liu, C Li… - Smart …, 2024 - Wiley Online Library
Abstract Donor‐acceptor (D‐A) compounds are particularly important in optoelectronic and
biological applications. However, they are normally synthesized in the presence of transition …