The excitement about nutrigenomics comes from a growing awareness of the potential for
modifications of food or diet to support health and reduce the risk of diet-related diseases. It …

Phase I and II drug metabolizing enzymes (DME) and drug transporters are involved in the
absorption, distribution, metabolism as well as elimination of many therapeutic agents …

Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme of folate pathway. Several
polymorphisms were reported in MTHFR gene but C677T polymorphism is most studied and …

Aim: We evaluated the pharmacogenetic influence of genetic polymorphisms in folate
pathway genes in Indian rheumatoid arthritis patients receiving methotrexate (MTX). Patients …

Background: Maternal folate, vitamin B-12, and vitamin B-6 concentrations during pregnancy
have been shown to influence birth outcomes, but the evidence is inconclusive. Objective …

Methotrexate (MTX), the most commonly used anti-rheumatic drug against RA, enters the
cell via the action of the reduced folate carrier 1 (RFC1). A major polymorphism of the RFC1 …

Ayurveda offers a unique opportunity to evolve a science of healthy, harmonious and long
life. Its holistic approach to health and disease, involving body, mind and spirit, can provide …

Objectives Methotrexate (MTX) is the most commonly used disease-modifying antirheumatic
drug for the treatment of rheumatoid arthritis (RA). Genetic polymorphisms of reduced folate …

Folic acid (FA) and iron are essential supplements during pregnancy. Similarly effects of
vitamin B12 (B12) inadequacy and high folate and low B12 status, on pregnancy outcome …

Methionine synthase reductase (MTRR) is an important enzyme of the folate/homocysteine
pathway. It is responsible for regulation of methionine enzyme by reductive methylation. A …