Heavy metal and metalloid-induced reproductive toxicity

AG Mukherjee, UR Wanjari, K Renu, B Vellingiri… - Environmental …, 2022 - Elsevier
Heavy metals and metalloid exposure are among the most common factors responsible for
reproductive toxicity in human beings. Several studies have indicated that numerous metals …

Antioxidants for male subfertility

W de Ligny, RM Smits… - Cochrane database …, 2022 - cochranelibrary.com
Background The inability to have children affects 10% to 15% of couples worldwide. A male
factor is estimated to account for up to half of the infertility cases with between 25% to 87% of …

Infertility in men: advances towards a comprehensive and integrative strategy for precision theranostics

M Assidi - Cells, 2022 - mdpi.com
Male infertility is an increasing and serious medical concern, though the mechanism
remains poorly understood. Impaired male reproductive function affects approximately half …

Oxidative stress and male infertility: the protective role of antioxidants

A Kaltsas - Medicina, 2023 - mdpi.com
Oxidative stress is a significant factor in male infertility, compromising sperm function and
overall reproductive health. As male infertility garners increasing attention, effective …

[HTML][HTML] Alpha-Lipoic Acid: Biological Mechanisms and Health Benefits

F Superti, R Russo - Antioxidants, 2024 - mdpi.com
Alpha-lipoic acid (ALA) is a bioactive molecule with significant health effects. The biological
action of ALA has been ascribed to the characteristic antioxidant properties of the oxidized …

[HTML][HTML] Effect of varicocelectomy on sperm deoxyribonucleic acid fragmentation rates in infertile men with clinical varicocele: a systematic review and meta-analysis

FTL Neto, M Roque, SC Esteves - Fertility and sterility, 2021 - Elsevier
Objective To evaluate the effect of varicocelectomy on sperm deoxyribonucleic acid
fragmentation (SDF) rates in infertile men with clinical varicocele. Design Systematic review …

Dietary antioxidants in the treatment of male infertility: counteracting oxidative stress

E Torres-Arce, B Vizmanos, N Babio… - Biology, 2021 - mdpi.com
Simple Summary The present review is a comprehensive description of reactive oxygen
species (ROS's) different sources, the re-productive consequences of excessive ROS and …

Does varicocele repair improve conventional semen parameters? A meta-analytic study of before-after data

R Cannarella, R Shah, TAAAM Hamoda… - The World Journal …, 2023 - pmc.ncbi.nlm.nih.gov
Purpose The purpose of this meta-analysis is to study the impact of varicocele repair in the
largest cohort of infertile males with clinical varicocele by including all available studies, with …

Oxidative versus reductive stress: a delicate balance for sperm integrity

N Sadeghi, G Boissonneault, M Tavalaee… - Systems biology in …, 2023 - Taylor & Francis
Despite the long-standing notion of “oxidative stress,” as the main mediator of many
diseases including male infertility induced by increased reactive oxygen species (ROS) …

[HTML][HTML] From pathophysiology to practice: addressing oxidative stress and sperm DNA fragmentation in Varicocele-affected subfertile men

FT Lira, LR Campos, M Roque, SC Esteves - International braz j urol, 2024 - SciELO Brasil
Varicocele can reduce male fertility potential through various oxidative stress mechanisms.
Excessive production of reactive oxygen species may overwhelm the sperm's defenses …