The Role of Porphyromonas gingivalis Outer Membrane Vesicles in Periodontal Disease and Related Systemic Diseases

Z Zhang, D Liu, S Liu, S Zhang, Y Pan - Frontiers in cellular and …, 2021 - frontiersin.org
Periodontal disease is a chronic infectious disease associated with a variety of bacteria,
which can cause damage to the periodontal support structure and affect a variety of systemic …

The infectious etiology of Alzheimer's disease

M Sochocka, K Zwolinska… - Current …, 2017 - ingentaconnect.com
Background: Inflammation is a part of the first line of defense of the body against invasive
pathogens, and plays a crucial role in tissue regeneration and repair. A proper inflammatory …

Viruses, periodontitis, and comorbidities

F Teles, RG Collman, D Mominkhan… - Periodontology …, 2022 - Wiley Online Library
Seminal studies published in the 1990s and 2000s explored connections between
periodontal diseases and systemic conditions, revealing potential contributions of …

Periodontitis and Alzheimer's disease: a possible comorbidity between oral chronic inflammatory condition and neuroinflammation

FB Teixeira, MT Saito, FC Matheus… - Frontiers in aging …, 2017 - frontiersin.org
Periodontitis is an oral chronic infection/inflammatory condition, identified as a source of
mediators of inflammation into the blood circulation, which may contribute to exacerbate …

[HTML][HTML] Infectious agents and Alzheimer's disease

T Piekut, M Hurła, N Banaszek, P Szejn… - Journal of Integrative …, 2022 - imrpress.com
Alzheimer's disease (AD) is the leading cause of dementia worldwide. Individuals affected
by the disease gradually lose their capacity for abstract thinking, understanding …

Association of inflammation and cognition in the elderly: a systematic review and meta-analysis

S Leonardo, F Fregni - Frontiers in Aging Neuroscience, 2023 - frontiersin.org
Background The development of mild cognitive impairment (MCI) and Alzheimer's disease
(AD) may be associated with an inflammatory process. Inflammatory cytokines may be a …

Oral microbiota and Alzheimer's disease: Do all roads lead to Rome?

A Sureda, M Daglia, SA Castilla, N Sanadgol… - Pharmacological …, 2020 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative pathology affecting milions of
people worldwide associated with deposition of senile plaques. While the genetic and …

Alzheimer disease and the periodontal patient: New insights, connections, and therapies

MI Ryder, P Xenoudi - Periodontology 2000, 2021 - Wiley Online Library
Loss of cognitive function in the aging population, particular those with Alzheimer disease,
presents unique challenges to health practitioners. For the dental practitioner these include …

Periodontitis Induced by P. gingivalis-LPS Is Associated With Neuroinflammation and Learning and Memory Impairment in Sprague-Dawley Rats

Y Hu, H Li, J Zhang, X Zhang, X Xia, C Qiu… - Frontiers in …, 2020 - frontiersin.org
Background Periodontitis is one of the most common oral diseases and is a potential risk
factor for systemic diseases. In this study, we aimed to investigate the association between …

[HTML][HTML] Association of periodontitis and oral microbiomes with Alzheimer's disease: A narrative systematic review

S Mao, CP Huang, H Lan, HG Lau, CP Chiang… - Journal of Dental …, 2022 - Elsevier
Background/purpose Alzheimer's disease (AD) is a neurodegenerative disorder and the
most common form of dementia. The etiology for AD includes age, genetic susceptibility …