Metrics of sleep apnea severity: beyond the apnea-hypopnea index

A Malhotra, I Ayappa, N Ayas, N Collop, D Kirsch… - Sleep, 2021 - academic.oup.com
Obstructive sleep apnea (OSA) is thought to affect almost 1 billion people worldwide. OSA
has well established cardiovascular and neurocognitive sequelae, although the optimal …

Obstructive sleep apnea: transition from pathophysiology to an integrative disease model

WT McNicholas, D Pevernagie - Journal of sleep research, 2022 - Wiley Online Library
Obstructive sleep apnea (OSA) is characterised by recurring episodes of upper airway
obstruction during sleep and the fundamental abnormality reflects the inability of the upper …

Randomized clinical trials of cardiovascular disease in obstructive sleep apnea: understanding and overcoming bias

AI Pack, UJ Magalang, B Singh, ST Kuna, BT Keenan… - Sleep, 2021 - academic.oup.com
Three recent randomized control trials (RCTs) found that treatment of obstructive sleep
apnea (OSA) with continuous positive airway pressure (CPAP) did not reduce rates of future …

Review and perspective on sleep-disordered breathing research and translation to clinics

H Korkalainen, S Kainulainen, AS Islind… - Sleep Medicine …, 2023 - Elsevier
Sleep-disordered breathing, ranging from habitual snoring to severe obstructive sleep
apnea, is a prevalent public health issue. Despite rising interest in sleep and awareness of …

Sleepiness in adults: An umbrella review of a complex construct

VP Martin, R Lopez, Y Dauvilliers, JL Rouas… - Sleep medicine …, 2023 - Elsevier
Sleepiness involves many dimensions that require investigation. Since sleepiness is often
defined operationally, we exhaustively inventoried all the assessment tools designed to …

Heart rate variability during wakefulness as a marker of obstructive sleep apnea severity

H Qin, BT Keenan, DR Mazzotti, F Vaquerizo-Villar… - Sleep, 2021 - academic.oup.com
Abstract Study Objectives Patients with obstructive sleep apnea (OSA) exhibit
heterogeneous heart rate variability (HRV) during wakefulness and sleep. We investigated …

A systematic analysis of ICSD-3 diagnostic criteria and proposal for further structured iteration

C Gauld, R Lopez, PA Geoffroy, CM Morin… - Sleep Medicine …, 2021 - Elsevier
The main objective of this theoretical review is to systematically analyze the type of
International Classification of Sleep Disorders-3 (ICSD-3) diagnostic criteria by labeling …

New and emerging approaches to better define sleep disruption and its consequences

B Lechat, H Scott, G Naik, K Hansen… - Frontiers in …, 2021 - frontiersin.org
Current approaches to quantify and diagnose sleep disorders and circadian rhythm
disruption are imprecise, laborious, and often do not relate well to key clinical and health …

Clinician-focused overview and developments in polysomnography

LC Markun, A Sampat - Current sleep medicine reports, 2020 - Springer
Abstract Purpose of Review Polysomnography (PSG) represents a fundamental diagnostic
tool used in the evaluation of sleep disorders. It represents a simultaneous recording of …

Characteristics and reproducibility of novel sleep EEG biomarkers and their variation with sleep apnea and insomnia in a large community-based cohort

M Younes, A Azarbarzin, M Reid, DR Mazzotti… - Sleep, 2021 - academic.oup.com
Abstract Study Objectives New electroencephalogram (EEG) features became available for
use in polysomnography and have shown promise in early studies. They include a …