Summary The 2015 Magnetic Resonance Imaging in Multiple Sclerosis and 2016
Consortium of Multiple Sclerosis Centres guidelines on the use of MRI in diagnosis and …

MRI has improved the diagnostic work-up of multiple sclerosis, but inappropriate image
interpretation and application of MRI diagnostic criteria contribute to misdiagnosis. Some …

To what extent does the subarachnoid cerebrospinal fluid (CSF) compartment communicate
directly with the extravascular compartment of human brain tissue? Interconnection between …

Multiple sclerosis is characterized by inflammatory activity that results in destruction of the
myelin sheaths that enwrap axons. The currently available medications for multiple sclerosis …

Pathological evaluation is the gold standard for identifying processes related to multiple
sclerosis that explain disease manifestations, and for guiding the development of new …

Histology permits the observation of otherwise invisible structures of the internal topography
of a specimen. Although it enables the investigation of tissues at a cellular level, it is invasive …

Neuroaxonal pathology is a main determinant of disease progression in multiple sclerosis;
however, its underlying pathophysiological mechanisms, including its link to inflammatory …

In recent years, the use of magnetic resonance imaging (MRI) for the diagnostic work-up of
multiple sclerosis (MS) has evolved considerably. The 2017 McDonald criteria show high …

Since its technical development in the early 1980s, magnetic resonance imaging (MRI) has
quickly been adopted as an essential tool in supporting the diagnosis, longitudinal …

Network science provides powerful access to essential organizational principles of the
human brain. It has been applied in combination with graph theory to characterize brain …