Structural and functional aspects of metal sites in biology
RH Holm, P Kennepohl, EI Solomon - Chemical reviews, 1996 - ACS Publications
The field of bioinorganic chemistry is at a propitious stage of development. Ever more
complex metallobiomolecules are isolated and purified, physical methodologies and …
complex metallobiomolecules are isolated and purified, physical methodologies and …
Matrix metalloproteinases (MMPs): Chemical–biological functions and (Q) SARs
RP Verma, C Hansch - Bioorganic & medicinal chemistry, 2007 - Elsevier
Matrix metalloproteinases (MMPs) are a large family of calcium-dependent zinc-containing
endopeptidases, which are responsible for the tissue remodeling and degradation of the …
endopeptidases, which are responsible for the tissue remodeling and degradation of the …
Recent advances in zinc enzymology
WN Lipscomb, N Sträter - Chemical Reviews, 1996 - ACS Publications
Posters and lectures presented at the Seventh International Conference on Bioinorganic
Chemistry (ICBIC) in Lubeck, Germany, last year was divided into 16 sections, including …
Chemistry (ICBIC) in Lubeck, Germany, last year was divided into 16 sections, including …
Zinc coordination sphere in biochemical zinc sites
DS Auld - Zinc biochemistry, physiology, and homeostasis: recent …, 2001 - Springer
Zinc is known to be indispensable to growth and development and transmission of the
genetic message. It does this through a remarkable mosaic of zinc binding motifs that …
genetic message. It does this through a remarkable mosaic of zinc binding motifs that …
Design and Therapeutic Application of Matrix Metalloproteinase Inhibitors. (Chem. Rev. 1999, 99, 2735−2776. Published on the Web September 8, 1999).
M Whittaker, CD Floyd, P Brown, AJH Gearing - Chemical reviews, 2001 - ACS Publications
[HTML][HTML] Matrix metalloproteinases: fold and function of their catalytic domains
C Tallant, A Marrero, FX Gomis-Rüth - Biochimica et Biophysica Acta (BBA) …, 2010 - Elsevier
Matrix metalloproteinases (MMPs) are zinc-dependent protein and peptide hydrolases. They
have been almost exclusively studied in vertebrates and 23 paralogs are present in humans …
have been almost exclusively studied in vertebrates and 23 paralogs are present in humans …
Molecular recognition of protein− ligand complexes: Applications to drug design
RE Babine, SL Bender - Chemical reviews, 1997 - ACS Publications
Advances in molecular biology have had a dramatic impact on the drug discovery process.
1, 2 The ability to produce recombinant proteins of biological significance has greatly …
1, 2 The ability to produce recombinant proteins of biological significance has greatly …
Inhibitors of gelatinases (MMP-2 and MMP-9) for the management of hematological malignancies
Abstract Matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9) are
collectively known as gelatinases whereas MMP-2 is gelatinase-A and MMP-9 is termed as …
collectively known as gelatinases whereas MMP-2 is gelatinase-A and MMP-9 is termed as …
Proteolytic remodeling of extracellular matrix
H Birkedal-Hansen - Current opinion in cell biology, 1995 - Elsevier
Matrix metalloproteinases and their natural inhibitors are ingredients of a fundamental
cellular toolbox for effecting environmental change. These enzymes enable cells to alter …
cellular toolbox for effecting environmental change. These enzymes enable cells to alter …
The metzincins—Topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a super family of zinc …
W Stöcker, F Grams, P Reinemer, W Bode… - Protein …, 1995 - Wiley Online Library
The three‐dimensional structures of the zinc endopeptidases human neutrophil
collagenase, adamalysin II from rattle snake venom, alkaline proteinase from Pseudomonas …
collagenase, adamalysin II from rattle snake venom, alkaline proteinase from Pseudomonas …