In vitro anti-cancer activity of a polyherbal preparation, VEDICINALS® 9, against A549 human lung adenocarcinoma cells

KR Paudel, R Rajput, G De Rubis, VSRR Allam… - … -Research and Practice, 2023 - Elsevier
Purpose Non-small cell lung cancer (NSCLC) is among the leading causes of morbidity and
mortality worldwide. Despite the availability of several treatment options, the five-year …

[HTML][HTML] Tumor-associated macrophages in non-small-cell lung cancer: from treatment resistance mechanisms to therapeutic targets

Z Huang, Z Xiao, L Yu, J Liu, Y Yang… - Critical Reviews in …, 2024 - Elsevier
Non-small cell lung cancer (NSCLC) remains one of the leading causes of cancer-related
deaths worldwide. Different treatment approaches are typically employed based on the …

[HTML][HTML] Strategies to Overcome Intrinsic and Acquired Resistance to Chemoradiotherapy in Head and Neck Cancer

T de Bakker, A Maes, T Dragan, P Martinive… - Cells, 2024 - mdpi.com
Definitive chemoradiotherapy (CRT) is a cornerstone of treatment for locoregionally
advanced head and neck cancer (HNC). Research is ongoing on how to improve the tumor …

USP7 promotes non‐small‐cell lung cancer cell glycolysis and survival by stabilizing and activating c‐Abl

Y He, S Jiang, Y Zhong, X Wang, Y Cui… - Clinical and …, 2023 - Wiley Online Library
Background Abelson tyrosine kinase (c‐Abl) is frequently mutated and highly expressed,
and promotes non‐small‐cell lung cancer (NSCLC) survival, metastasis and tumorigenesis …

[HTML][HTML] DNA Damage and Inflammatory Response of p53 Null H358 Non-Small Cell Lung Cancer Cells to X-Ray Exposure Under Chronic Hypoxia

H Nisar, M Brauny, FM Labonté, C Schmitz… - International Journal of …, 2024 - mdpi.com
Hypoxia-induced radioresistance limits therapeutic success in cancer. In addition, p53
mutations are widespread in tumors including non-small cell lung carcinomas (NSCLCs) …

Hypoxia Modulates Radiosensitivity and Response to Different Radiation Qualities in A549 Non-Small Cell Lung Cancer (NSCLC) Cells

H Nisar, FM Labonté, MD Roggan, C Schmitz… - International Journal of …, 2024 - mdpi.com
Hypoxia-induced radioresistance reduces the efficacy of radiotherapy for solid
malignancies, including non-small cell lung cancer (NSCLC). Cellular hypoxia can confer …

Differential effects of hypoxia on motility using various in vitro models of lung adenocarcinoma

SE Surguta, M Baranyi, L Svajda, M Cserepes… - Scientific Reports, 2024 - nature.com
Lung cancer is the leading cause of cancer-related death globally. Metastasis is the most
common reason of mortality in which hypoxia is suggested to have a pivotal role. However …

Influence of lactate in resistance to anti‑PD‑1/PD‑L1 therapy: Mechanisms and clinical applications

Y Zeng, Y Huang, Q Tan, L Peng… - Molecular …, 2024 - spandidos-publications.com
Metabolic reprogramming is a prominent characteristic of tumor cells, evidenced by
heightened secretion of lactate, which is linked to tumor progression. Furthermore, the …

Hypoxia studies in non‑small cell lung cancer: Pathogenesis and clinical implications

S Zhou, J Sun, W Zhu, Z Yang… - Oncology …, 2024 - spandidos-publications.com
Non-small cell lung cancer (NSCLC) is one of the most prevalent and lethal types of cancers
worldwide and its high incidence and mortality rates pose a significant public health …

[HTML][HTML] A computational discovery of hexokinase 2 inhibitors from Newbouldia laevis for Hepatocellular carcinoma (HCC) treatment

HA Adekilekun, HA Oyewusi, RA Wahab… - South African Journal of …, 2024 - Elsevier
Newbouldia laevis, also known as the African Border Tree or Fever Tree, is a deciduous tree
native to West Africa. The plant is valued for its medicinal properties and is used in …