Deep learning for lung cancer diagnosis, prognosis and prediction using histological and cytological images: a systematic review

A Davri, E Birbas, T Kanavos, G Ntritsos, N Giannakeas… - Cancers, 2023 - mdpi.com
Simple Summary Lung cancer is one of the most common and deadly malignancies
worldwide. Microscopic examination of histological and cytological lung specimens can be a …

Evaluating cancer-related biomarkers based on pathological images: a systematic review

X Xie, X Wang, Y Liang, J Yang, Y Wu, L Li… - Frontiers in …, 2021 - frontiersin.org
Many diseases are accompanied by changes in certain biochemical indicators called
biomarkers in cells or tissues. A variety of biomarkers, including proteins, nucleic acids …

The impact of site-specific digital histology signatures on deep learning model accuracy and bias

FM Howard, J Dolezal, S Kochanny, J Schulte… - Nature …, 2021 - nature.com
Abstract The Cancer Genome Atlas (TCGA) is one of the largest biorepositories of digital
histology. Deep learning (DL) models have been trained on TCGA to predict numerous …

[HTML][HTML] Prediction of HER2-positive breast cancer recurrence and metastasis risk from histopathological images and clinical information via multimodal deep learning

J Yang, J Ju, L Guo, B Ji, S Shi, Z Yang, S Gao… - Computational and …, 2022 - Elsevier
HER2-positive breast cancer is a highly heterogeneous tumor, and about 30% of patients
still suffer from recurrence and metastasis after trastuzumab targeted therapy. Predicting …

Uncertainty-informed deep learning models enable high-confidence predictions for digital histopathology

JM Dolezal, A Srisuwananukorn, D Karpeyev… - Nature …, 2022 - nature.com
A model's ability to express its own predictive uncertainty is an essential attribute for
maintaining clinical user confidence as computational biomarkers are deployed into real …

An enhanced histopathology analysis: An ai-based system for multiclass grading of oral squamous cell carcinoma and segmenting of epithelial and stromal tissue

J Musulin, D Štifanić, A Zulijani, T Ćabov, A Dekanić… - Cancers, 2021 - mdpi.com
Simple Summary An established dataset of histopathology images obtained by biopsy and
reviewed by two pathologists is used to create a two-stage oral squamous cell carcinoma …

Predicting colorectal cancer tumor mutational burden from histopathological images and clinical information using multi-modal deep learning

K Huang, B Lin, J Liu, Y Liu, J Li, G Tian, J Yang - Bioinformatics, 2022 - academic.oup.com
Motivation Tumor mutational burden (TMB) is an indicator of the efficacy and prognosis of
immune checkpoint therapy in colorectal cancer (CRC). In general, patients with higher TMB …

ICSDA: a multi-modal deep learning model to predict breast cancer recurrence and metastasis risk by integrating pathological, clinical and gene expression data

Y Yao, Y Lv, L Tong, Y Liang, S Xi, B Ji… - Briefings in …, 2022 - academic.oup.com
Breast cancer patients often have recurrence and metastasis after surgery. Predicting the
risk of recurrence and metastasis for a breast cancer patient is essential for the development …

Deep-learning algorithm and concomitant biomarker identification for NSCLC prediction using multi-omics data integration

MK Park, JM Lim, J Jeong, Y Jang, JW Lee, JC Lee… - Biomolecules, 2022 - mdpi.com
Early diagnosis of lung cancer to increase the survival rate, which is currently at a low range
of mid-30%, remains a critical need. Despite this, multi-omics data have rarely been applied …

DeepRePath: identifying the prognostic features of early-stage lung adenocarcinoma using multi-scale pathology images and deep convolutional neural networks

WS Shim, K Yim, TJ Kim, YE Sung, G Lee, JH Hong… - Cancers, 2021 - mdpi.com
Simple Summary Pathology images are vital for understanding solid cancers. In this study,
we created DeepRePath using multi-scale pathology images with two-channel deep …