After ischaemic cerebral vascular injury, efferocytosis—a process known as the efficient
clearance of apoptotic cells (ACs) by various phagocytes in both physiological and …

Efferocytosis is a crucial process whereby phagocytes engulf and eliminate apoptotic cells
(ACs). This intricate process can be categorized into four steps:(1) ACs release “find me” …

The role of pro-inflammatory macrophages (M1) in rheumatoid arthritis (RA) is significant, as
they produce excessive cytokines. Targeting efferocytosis is a potential manner to repolarize …

Objective Chronic inflammation and oxidative stress mediate the pathological progression of
diabetic complications, like diabetic retinopathy (DR), peripheral neuropathy (DPN) and …

Abstract AMPK (Adenosine 5'-Monophosphate activated Protein Kinase) functions as a
fundamental regulator of glycolipid metabolism by regulating the rate-limiting enzyme …

Background Alzheimer's disease (AD) is a neurodegenerative disease characterized by the
accumulation of amyloid beta (Aβ) and tau aggregates within the neuronal milieu. To …

摘要背景: 巨噬细胞胞葬作用障碍引起的局部和系统炎症损害与多种肥胖相关代谢性疾病有关,
且以胞葬作用为靶向的化合物表现出良好的治疗效果. 目的: 通过综述肥胖对巨噬细胞胞葬作用 …

BACKGROUND: Dysfunction of macrophage efferocytosis can induce local and systemic
inflammatory damage and is associated with a variety of obesity-related metabolic diseases …