[HTML][HTML] The trinity of cGAS, TLR9, and ALRs guardians of the cellular galaxy against host-derived self-DNA

V Kumar - Frontiers in Immunology, 2021 - frontiersin.org
The immune system has evolved to protect the host from the pathogens and allergens
surrounding their environment. The immune system develops in such a way to recognize …

[HTML][HTML] Role of TLRs in HIV-1 infection and potential of TLR agonists in HIV-1 vaccine development and treatment strategies

M Rozman, S Zidovec-Lepej, K Jambrosic, M Babić… - Pathogens, 2023 - mdpi.com
Toll-like receptors (TLRs), as a family of pattern recognition receptors, play an important role
in the recognition of HIV-1 molecular structures by various cells of the innate immune …

[HTML][HTML] The toll-like receptor 4 polymorphism Asp299Gly is associated with an increased risk of ovarian cancer

KD Kania, D Haręża, JR Wilczyński, M Wilczyński… - Cells, 2022 - mdpi.com
Ovarian cancer (OC) is one of the most common cancers threatening women's lives around
the world. Epithelial ovarian tumors represent the most common ovarian neoplasms. Most …

[HTML][HTML] High-Risk Human Papillomavirus and Epstein–Barr Virus Coinfection: A Potential Role in Head and Neck Carcinogenesis

R Blanco, D Carrillo-Beltrán, AH Corvalán, F Aguayo - Biology, 2021 - mdpi.com
Simple Summary A subset of carcinomas that arise in the head and neck region show a viral
etiology. In fact, a subgroup of oropharyngeal cancers are caused by some types of human …

[HTML][HTML] Pathogenesis and therapeutic implications of EBV-associated epithelial cancers

YH Low, CJL Loh, DYY Peh, AJM Chu, S Han… - Frontiers in …, 2023 - frontiersin.org
Epstein-Barr virus (EBV), one of the most common human viruses, has been associated with
both lymphoid and epithelial cancers. Undifferentiated nasopharyngeal carcinoma (NPC) …

[HTML][HTML] Influence of single-nucleotide polymorphisms in TLR3 (rs3775291) and TLR9 (rs352139) on the risk of CMV infection in kidney transplant recipients

N Redondo, I Rodríguez-Goncer, P Parra… - Frontiers in …, 2022 - frontiersin.org
Risk stratification for cytomegalovirus (CMV) infection after kidney transplantation (KT)
remains to be determined. Since endosomal toll-like receptors (TLRs) are involved in viral …

Involvement of TLR4 in Acute Hepatitis Associated with Airway Infection of Murine γ-Herpesvirus 68

K Kanai, S Kageyama, O Yoshie - The Journal of Immunology, 2023 - journals.aai.org
Extrahepatic viral infections are often accompanied by acute hepatitis, as evidenced by
elevated serum liver enzymes and intrasinusoidal infiltration of CD8+ T cells, without direct …

[HTML][HTML] Association of toll-like receptors in malaria susceptibility and immunopathogenesis: A meta-analysis

ADR Ramirez, MCS de Jesus, J Rossit, NF Reis… - Heliyon, 2022 - cell.com
Toll-like receptors (TLRs) play a key role in the induced immune response in malaria.
Although the potential roles of TLRs have been described, it is necessary to elucidate which …

Epstein-Barr virus infectious particles initiate B cell transformation and modulate cytokine response

F Baccianti, C Masson, S Delecluse, Z Li, R Poirey… - Mbio, 2023 - Am Soc Microbiol
ABSTRACT The Epstein-Barr virus (EBV) efficiently transforms primary B cells. Here, we
show that this process starts immediately after cellular exposure to infectious viral particles …

[HTML][HTML] Comparison of COVID-19 characteristics in Egyptian patients according to their Toll-Like Receptor-4 (Asp299Gly) polymorphism

SI Taha, AK Shata, EM El-Sehsah… - Le Infezioni in …, 2022 - ncbi.nlm.nih.gov
Background Toll-like receptor (TLR)-4 plays a vital role in recognizing viral particles,
activating the innate immune system, and producing pro-inflammatory cytokines. Objectives …