[HTML][HTML] Revealing the mystery of persistent smell loss in Long COVID patients

JW Park, X Wang, RH Xu - International Journal of Biological …, 2022 - ncbi.nlm.nih.gov
COVID-19 is hopefully approaching its end in many countries as herd immunity develops
and weaker strains of SARS-CoV-2 dominate. However, a new concern occurs over the long …

[HTML][HTML] Olfactory neuropathology in Alzheimer's disease: a sign of ongoing neurodegeneration

G Son, A Jahanshahi, SJ Yoo, JT Boonstra… - BMB …, 2021 - ncbi.nlm.nih.gov
Olfactory neuropathology is a cause of olfactory loss in Alzheimer's disease (AD). Olfactory
dysfunction is also associated with memory and cognitive dysfunction and is an incidental …

A nasal cell atlas reveals heterogeneity of tuft cells and their role in directing olfactory stem cell proliferation

S Ualiyeva, E Lemire, C Wong, A Perniss… - Science …, 2024 - science.org
The olfactory neuroepithelium serves as a sensory organ for odors and forms part of the
nasal mucosal barrier. Olfactory sensory neurons are surrounded and supported by …

Integrated age‐related immunohistological changes occur in human olfactory epithelium and olfactory bulb

M Fitzek, PK Patel, PD Solomon, B Lin… - Journal of …, 2022 - Wiley Online Library
Olfactory epithelium (OE) is capable of lifelong regeneration due to presence of basal
progenitor cells that respond to injury or neuronal loss with increased activity. However, this …

Chronic interleukin‐13 expression in mouse olfactory mucosa results in regional aneuronal epithelium

A Saraswathula, MM Liu, H Kulaga… - International forum of …, 2023 - Wiley Online Library
Background Olfactory dysfunction is highly associated with chronic rhinosinusitis with nasal
polyps (CRSwNP), and the severity of loss has been linked with biomarkers of type 2 …

The neuroregenerative capacity of olfactory stem cells is not limitless: implications for aging

KM Child, DB Herrick, JE Schwob… - Journal of …, 2018 - Soc Neuroscience
The olfactory epithelium (OE) of vertebrates is a highly regenerative neuroepithelium that is
maintained under normal conditions by a population of stem and progenitor cells, globose …

Regeneration and rewiring of rodent olfactory sensory neurons

CR Yu, Y Wu - Experimental neurology, 2017 - Elsevier
The olfactory sensory neurons are the only neurons in the mammalian nervous system that
not only regenerate naturally and in response to injury, but also project to specific targets in …

Cell type-and layer-specific plasticity of olfactory bulb interneurons following olfactory sensory neuron ablation

T Kunkhyen, TR Brechbill, SPR Berg, P Pothuri… - Scientific Reports, 2024 - nature.com
Lifelong neurogenesis endows the mouse olfactory system with a capacity for regeneration
that is unique in the mammalian nervous system. Throughout life, olfactory sensory neurons …

Isolation and differentiation of neurons and glial cells from olfactory epithelium in living subjects

P Unzueta-Larrinaga, R Barrena-Barbadillo… - Molecular …, 2023 - Springer
The study of psychiatric and neurological diseases requires the substrate in which the
disorders occur, that is, the nervous tissue. Currently, several types of human bio-specimens …

A molecular analysis of neural olfactory placode differentiation in human pluripotent stem cells

RL Bricker, U Bhaskar, R Titone… - Stem Cells and …, 2022 - liebertpub.com
During embryonic development, the olfactory sensory neurons (OSNs) and the gonadotropic-
releasing hormone neurons (GNRHNs) migrate from the early nasal cavity, known as the …