The remarkable impact of mRNA vaccines on mitigating disease and improving public
health has been amply demonstrated during the COVID-19 pandemic. Many new mRNA …

In the food industry, drying is a crucial unit process for extending product shelf life. Many
methods are available for drying of foods but spray drying and freeze drying have been …

Messenger RNA (mRNA) lipid nanoparticles (LNPs) have emerged at the forefront during
the COVID-19 vaccination campaign. Despite their tremendous success, mRNA vaccines …

The COVID-19 pandemic has underscored the critical importance of adaptable and resilient
public health systems capable of rapid response to emerging health crises. This paper …

Introduction Messenger ribonucleic acid (mRNA) and small interfering RNA (siRNA) are
biological molecules that can be heated, frozen, lyophilized, precipitated, or re-suspended …

Pulmonary infections (PIs) are contributing as a significant cause of mortality across the
world. The clinical applications of a variety of therapeutics approved for PIs have been …

The de novo construction of a living organism is a compelling vision. Despite the astonishing
technologies developed to modify living cells, building a functioning cell “from scratch” has …

The remarkable success of two FDA-approved mRNA-encapsulating vaccines (Comirnaty®
and Spikevax®) indicated the importance of lipid nanoparticles (LNPs) delivery systems in …

The surface drying process is an important technology in the pharmaceutical, biomedical,
and food industries. The final stage of formulation development (ie, the drying process) faces …

Various biopharmaceutical products are distributed as freeze-dried formulations in vials.
Minimizing batch heterogeneity, which refers to the variability of relevant properties among …