Selenium deficiency caused fibrosis as an oxidative stress-induced inflammatory injury in the lungs of mice

Y Fu, Y Wang, Q Bu, M Guo - Biological Trace Element Research, 2023 - Springer
Selenium (Se) is a vital trace element in the regulation of inflammation and antioxidant
reactions in both animals and humans. Se deficiency is rapidly affecting lung function. The …

BMSC‐Derived Exosomes Alleviate Intervertebral Disc Degeneration by Modulating AKT/mTOR‐Mediated Autophagy of Nucleus Pulposus Cells

Q Xiao, Z Zhao, Y Teng, L Wu, J Wang… - Stem cells …, 2022 - Wiley Online Library
The pathogenesis of intervertebral disc degeneration (IDD) is still unclear. It has been
shown that the pathological process of IDD is most closely related to inflammation of nucleus …

Nucleus pulposus cell network modelling in the intervertebral disc

S Tseranidou, M Segarra-Queralt… - npj Systems Biology …, 2025 - nature.com
Intervertebral disc degeneration (IDD) results from an imbalance between anabolic and
catabolic processes in the extracellular matrix (ECM). Due to complex biochemical …

Acamprosate effect on neuropathic pain in rats: With emphasis on the role of ERK/MAPK pathway and SCN9A sodium channel

Z Abbasi, T Baluchnejadmojarad, M Roghani… - Journal of Chemical …, 2023 - Elsevier
Background Neuropathic pain is a chronic pain owing to nerve damage or diseases of the
central nervous system (CNS). The expression of SCN9A, which encodes the Nav1. 7 …

Bag-1 Protects Nucleus Pulposus Cells from Oxidative Stress by Interacting with HSP70

K Suyama, D Sakai, S Hayashi, N Qu, H Terayama… - Biomedicines, 2023 - mdpi.com
Bcl-2-associated athanogene 1 (Bag-1) is a multifunctional prosurvival protein that binds to
several intracellular targets and promotes cell survival. HSP70 and Raf-1 are important …

[PDF][PDF] Global trends in disc degeneration and degenerative disc disease: a bibliometric and visualization study

L Changsheng, W Weiwei, Y Su, L Xiyong… - Frontiers in Medical …, 2023 - francis-press.com
Objective: There has been increasing interest in the study of disc degeneration and
degenerative disc disease. The purpose of this study was to investigate the global status …