Glycosylation is one of the most important post-translational modifications of proteins and
plays an essential role in spermatogenesis, maturation, extracellular quality control …

Retrieving spermatozoa from the testicles has been a great hope for patients with non-
obstructive azoospermia (NOA), but relevant methods have not yet been developed to the …

Diabetes mellitus (DM) is a complex metabolic disease and it is also closely associated with
a reduction in fertility in male patients. The purpose of the present study was to investigate …

Eif2s3y (eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked, Eif2s3y)
is an essential gene for spermatogenesis. Early studies have shown that Eif2s3y can …

Male factor infertility affects 50% of infertile couples worldwide; the most severe form, non-
obstructive azoospermia (NOA), affects 10–15% of infertile males. Treatment for individuals …

Blood–testis barrier (BTB) is critical for maintaining fertility. The integrity of tight junctions
(TJs) provides restricted permeability of BTB. The aim of this study was to evaluate the …

Spermatogenesis is initiated when spermatogonial stem cells (SSCs) in the mature testes
enter mitosis and trigger differentiation. Thus, spermatogenesis and the ability to maintain a …

Asthenozoospermia is the most common clinical symptom of male infertility. Molecular
markers associated with asthenozoospermia spermatozoa are scarcely identified. The …

Metalloproteinases include matrix metalloproteinases and disintegrin metalloproteinases.
They are important members of the ECM degradation and reconstruction process and are …

Abstract Development of a functional gonad includes migration of primordial germ cells
(PGCs), differentiations of somatic and germ cells, formation of primary follicles or …