Common Pathophysiology in Cancer, Atrial Fibrillation, Atherosclerosis, and Thrombosis: JACC: CardioOncology State-of-the-Art Review

O Leiva, D AbdelHameid, JM Connors, CP Cannon… - Cardio Oncology, 2021 - jacc.org
Cardiovascular disease and cancer are the 2 leading causes of death worldwide. Emerging
evidence suggests common mechanisms between cancer and cardiovascular disease …

Atrial fibrillation and myocardial infarction: a systematic review and appraisal of pathophysiologic mechanisms

F Violi, EZ Soliman, P Pignatelli… - Journal of the American …, 2016 - Am Heart Assoc
Background A growing body of evidence suggests that atrial fibrillation (AF) is associated
with myocardial infarction (MI). However, incidence and management of MI in AF is still …

Gut‐derived serum lipopolysaccharide is associated with enhanced risk of major adverse cardiovascular events in atrial fibrillation: Effect of adherence to …

D Pastori, R Carnevale, C Nocella, M Novo… - Journal of the …, 2017 - Am Heart Assoc
Background Gut microbiota is emerging as a novel risk factor for atherothrombosis, but the
predictive role of gut‐derived lipopolysaccharide (LPS) is unknown. We analyzed (1) the …

Prostanoid metabolites as biomarkers in human disease

H Idborg, SC Pawelzik - Metabolites, 2022 - mdpi.com
Prostaglandins (PGD2, PGE2, PGF2α), prostacyclin (PGI2), and thromboxane A2 (TXA2)
together form the prostanoid family of lipid mediators. As autacoids, these five primary …

Relationship of PCSK9 and urinary thromboxane excretion to cardiovascular events in patients with atrial fibrillation

D Pastori, C Nocella, A Farcomeni… - Journal of the American …, 2017 - jacc.org
Background: Soluble proprotein convertase subtilisin/kexin type 9 (PCSK9) has been shown
to be predictive of cardiovascular events (CVEs) in patients who are at high cardiovascular …

A randomized placebo controlled trial of aspirin effects on immune activation in chronically human immunodeficiency virus-infected adults on virologically suppressive …

MP O'Brien, PW Hunt, DW Kitch… - Open forum …, 2017 - academic.oup.com
Background Immune activation persists despite suppressive antiretroviral therapy (ART) in
human immunodeficiency virus (HIV) infection and predicts non-Acquired Immune …

Statin use and mortality in atrial fibrillation: A systematic review and meta-analysis of 100,287 patients

D Pastori, F Baratta, A Di Rocco, A Farcomeni… - Pharmacological …, 2021 - Elsevier
Statins are effective for reducing cardiovascular disease in patients at risk or with
cardiovascular disease. The benefit of statin therapy on adverse cardiovascular outcomes in …

Stroke and bleeding risk assessments in patients with atrial fibrillation: concepts and controversies

WY Ding, S Harrison, D Gupta, GYH Lip… - Frontiers in …, 2020 - frontiersin.org
Risk assessments are an important element in the management of patients with atrial
fibrillation (AF). In this review, we aim to discuss the concepts and controversies surrounding …

Aging‐related decline of glutathione peroxidase 3 and risk of cardiovascular events in patients with atrial fibrillation

D Pastori, P Pignatelli, A Farcomeni… - Journal of the …, 2016 - Am Heart Assoc
Background Experimental studies demonstrated that glutathione peroxidase 3 (GP x3), an
antioxidant enzyme that catabolizes hydrogen peroxide, protects against thrombosis. Little is …

Impact of preexisting diabetes mellitus on cardiovascular and all-cause mortality in patients with atrial fibrillation: A meta-analysis

J Xu, Y Sun, D Gong, Y Fan - Frontiers in Endocrinology, 2022 - frontiersin.org
Objective To determine the impact of preexisting diabetes mellitus on cardiovascular and all-
cause mortality in patients with atrial fibrillation (AF) by conducting a meta-analysis. Methods …