The stereochemical activity of the 6s 2 lone pair has profound consequences on the
coordination chemistry of metal ions like Tl+, Pb 2+ and Bi 3+. The coordination chemistry of …

This article provides an overview of preclinical theranostic radiopharmaceutical
development, highlighting aspects of the preclinical development stages that can lead …

Background Recently, radiotheranostics comprising the true matched radionuclide pair
203/212Pb could serve as real dosimetric planning utility using 203Pb-radiolabelled …

Purpose The radionuclide pair cerium-134/lanthanum-134 (134Ce/134La) was recently
proposed as a suitable diagnostic counterpart for the therapeutic alpha-emitter actinium-225 …

With increasing clinical applications and interest in targeted alpha therapy, there is growing
interest in developing alternative chelating agents for [212Pb] Pb2+ and [212/213Bi] Bi3+ …

Rationale: 212Pb, a promising in vivo alpha-particle generator of 212Bi, has aroused much
interest as a therapeutic radionuclide. For the development of targeted alpha therapy (TAT) …

To enhance the affinity of peptide ligands for their targets, covalent warheads can be
engineered to facilitate irreversible binding. This study aimed at exploring the potential of a …

We present a detailed investigation on the coordination chemistry of [nat/203Pb] Pb (II) with
chelators H4PYTA and H4CHX‐PYTA. These chelators belong to the family of ligands …

On stage, and in real life, timing is critical for success. Theranostic cancer care epitomizes
the central role of timing in the evolution of efficacious molecular targeted radioligand …

An innovative cloud point extraction (CPE) method was proposed for the extraction and
enrichment of medically valuable radionuclide lead-212 (212Pb) from thorium decay series …