Dendritic-cell-vaccine-based immunotherapy for hepatocellular carcinoma: clinical trials and recent preclinical studies

LB Jeng, LY Liao, FY Shih, CF Teng - Cancers, 2022 - mdpi.com
Simple Summary This review summarizes the evidence from clinical trials and recent
preclinical studies regarding the evaluation and optimization of dendritic cells (DCs)-based …

Atypical immunometabolism and metabolic reprogramming in liver cancer: Deciphering the role of gut microbiome

RM Golonka, M Vijay-Kumar - Advances in cancer research, 2021 - Elsevier
Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related mortality
worldwide. Much recent research has delved into understanding the underlying molecular …

Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+ T cells

J Sprooten, I Vanmeerbeek, A Datsi, J Govaerts… - Cell Reports …, 2024 - cell.com
Current immunotherapies provide limited benefits against T cell-depleted tumors, calling for
therapeutic innovation. Using multi-omics integration of cancer patient data, we predict a …

Boron derivatives inhibit the proliferation of breast cancer cells and affect tumor-specific T cell activity in vitro by distinct mechanisms

EE Mohammed, N Türkel, UM Yigit, AB Dalan… - … Trace Element Research, 2023 - Springer
Breast cancer is the most frequently diagnosed cancer among women worldwide. Despite
the initial clinical response obtained with the widely used conventional chemotherapy, an …

Machine learning-based disulfidptosis-related lncRNA signature predicts prognosis, immune infiltration and drug sensitivity in hepatocellular carcinoma

L Pu, Y Sun, C Pu, X Zhang, D Wang, X Liu, P Guo… - Scientific Reports, 2024 - nature.com
Disulfidptosis a new cell death mode, which can cause the death of Hepatocellular
Carcinoma (HCC) cells. However, the significance of disulfidptosis-related Long non-coding …

Correlation between the changes of serum COX 2, APE1, VEGF, TGF-β and TSGF levels and prognosis in patients with osteosarcoma before and after treatment

Q Zhang, G Dong, F Wang, W Ding - Journal of Cancer Research …, 2020 - journals.lww.com
Aims: The aim of this study is to investigate the correlation between changes in serum
cyclooxygenase-2 (COX-2), basic fibroblast growth factor (bFGF), vascular endothelial …

Innovative molecular subtypes of multiple signaling pathways in colon cancer and validation of FMOD as a prognostic-related marker

Z Dai, X Peng, X Cui, Y Guo, J Zhang, X Shen… - Journal of Cancer …, 2023 - Springer
Purpose Colon cancer is highly heterogeneous in terms of the immune and stromal
microenvironment, genomic integrity, and oncogenic properties; therefore, molecular …

Predictive value of serum alkaline phosphatase, tumor-specific growth factor, and macrophage migration inhibitory factor for the efficacy of immunotargeted therapy in …

N Ding, X Fan, H Guo, D Xue… - American Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Objective: To assess the predictive value of serum alkaline phosphatase (ALP), tumor-
specific growth factor (TSGF), and macrophage migration inhibitory factor (MIF) for the …

[HTML][HTML] Anoikis-related lncRNA signature predicts prognosis and is associated with immune infiltration in hepatocellular carcinoma

J Zhu, W Zhao, J Yang, C Liu, Y Wang… - Anti-Cancer …, 2024 - journals.lww.com
Anoikis is a programmed cell death process triggered when cells are dislodged from the
extracellular matrix. Numerous long noncoding RNAs (lncRNAs) have been identified as …

Identification of HLA-A2 restricted epitopes of glypican-3 and induction of CTL responses in HLA-A2 transgenic mice

X Jin, X Liu, Z Zhou, Y Ding, Y Wu, J Qiu… - Cancer Immunology …, 2022 - Springer
Hepatocellular carcinoma (HCC) is a malignant tumor with high mortality, but lacks effective
treatments. Carcinoembryonic antigen glypican-3 (GPC3) is a tumor-associated antigen …