Neurocognitive impairment in Huntington's disease (HD) frequently includes deficits in
emotion recognition, and recent studies have also provided evidence for deficits in theory of …

Clinical populations with basal ganglia pathologies may present with language production
impairments, which are often described in combination with comprehension measures or …

Phenotypic manifestations of Huntington disease (HD) can be detected at least 15 years
prior to the time when a motor diagnosis is given. Advances in clinical care and future …

Accumulating evidence highlights the potential role of mixed proteinopathies (ie, abnormal
protein aggregation) in the development of clinical manifestations of neurodegenerative …

Background: Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative
disease. Executive dysfunction is common in patients with ALS, with up to 50% of patients …

Much of human interaction is predicated upon our innate capacity to infer the thoughts,
beliefs, emotions, and perspectives of others, in short, to possess a “theory of mind”(ToM) …

Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by
an abnormal CAG expansion in exon 1 of the huntingtin (HTT) gene. Given its genetic basis …

Objective Determining the sequence in which Huntington's disease biomarkers become
abnormal can provide important insights into the disease progression and a quantitative tool …

Amyotrophic lateral sclerosis (ALS) is associated with executive dysfunction and
behavioural impairment. Recent studies suggested that social cognitive deficits might also …

Background Cognitive disturbances occur early in Huntington's disease (HD) and place a
significant burden on the lives of patients and family members. Whilst these impairments are …