MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

Small RNAs of 20–30 nucleotides can target both chromatin and transcripts, and thereby
keep both the genome and the transcriptome under extensive surveillance. Recent progress …

Aneuploidy, an abnormal chromosome composition, is a major contributor to cancer
development and progression and an important determinant of cancer therapeutic …

MicroRNAs (miRNAs) comprise species of short noncoding RNA that regulate gene
expression post‐transcriptionally. Recent studies have demonstrated that epigenetic …

MicroRNAs (miRNAs) have emerged as key post-transcriptional regulators of gene
expression, involved in diverse physiological and pathological processes. Although miRNAs …

MicroRNAs (miRNAs) may be important regulators of gene expression. By modulating
oncogenic and tumor suppressor pathways they could, in principle, contribute to …

Appropriate patterns of DNA methylation and histone modifications are required to assure
cell identity, and their deregulation can contribute to human diseases, such as cancer. Our …

MicroRNAs (miRNAs) are a class of small non-coding RNAs that, in general, negatively
regulate gene expression. They have been identified in various tumor types, showing that …

The BCR-ABL1 oncoprotein transforms pluripotent HSCs and initiates chronic myeloid
leukemia (CML). Patients with early phase (also known as chronic phase [CP]) disease …

MicroRNAs and heterogeneous ribonucleoproteins (hnRNPs) are posttranscriptional gene
regulators that bind mRNA in a sequence-specific manner. Here, we report that loss of miR …