Neurotensin: role in psychiatric and neurological diseases
R Cáceda, B Kinkead, CB Nemeroff - Peptides, 2006 - Elsevier
Neurotensin (NT), an endogenous brain–gut peptide, has a close anatomical and functional
relationship with the mesocorticolimbic and neostriatal dopamine system. Dysregulation of …
relationship with the mesocorticolimbic and neostriatal dopamine system. Dysregulation of …
Ventral tegmental area neurotensin signaling links the lateral hypothalamus to locomotor activity and striatal dopamine efflux in male mice
CM Patterson, JMT Wong, GM Leinninger… - …, 2015 - academic.oup.com
Projections from the lateral hypothalamic area (LHA) innervate components of the
mesolimbic dopamine (MLDA) system, including the ventral tegmental area (VTA) and …
mesolimbic dopamine (MLDA) system, including the ventral tegmental area (VTA) and …
The neurotensin agonist PD149163 increases Fos expression in the prefrontal cortex of the rat
KA Petrie, M Bubser, CD Casey, MD Davis… - …, 2004 - nature.com
Dopaminergic axons innervating the prefrontal cortex (PFC) target both pyramidal cells and
GABAergic interneurons. Many of these dopamine (DA) axons in the rat coexpress the …
GABAergic interneurons. Many of these dopamine (DA) axons in the rat coexpress the …
Antagonism of neurotensin receptors in the ventral tegmental area decreases methamphetamine self-administration and methamphetamine seeking in mice
S Dominguez-Lopez, E Piccart… - International Journal …, 2018 - academic.oup.com
Background Neurotensin is a peptide that modulates central dopamine neurotransmission
and dopamine-related behaviors. Methamphetamine self-administration increases …
and dopamine-related behaviors. Methamphetamine self-administration increases …
Endogenous neurotensin in the ventral tegmental area contributes to amphetamine behavioral sensitization
F Panayi, J Colussi-Mas, L Lambás-Senas… - …, 2005 - nature.com
Studies showing psychostimulant-like effects of exogenous neurotensin (NT) infused into the
ventral tegmental area (VTA) prompted us to examine the role in the VTA of the endogenous …
ventral tegmental area (VTA) prompted us to examine the role in the VTA of the endogenous …
Specific involvement of neurotensin type 1 receptor in the neurotensin‐mediated in vivo dopamine efflux using knock‐out mice
M Leonetti, P Brun, M Clerget… - Journal of …, 2004 - Wiley Online Library
Neurotensin is a tridecapeptide neurotransmitter known to be involved in psychiatric
disorders, various physiological processes and several different neurobiological …
disorders, various physiological processes and several different neurobiological …
In vivo monitoring of dopamine overflow in the central nervous system by amperometric techniques combined with carbon fibre electrodes
MF Suaud-Chagny - Methods, 2004 - Elsevier
Electrochemical techniques are extensively used to investigate in vivo and in vitro events
associated with neurotransmission, particularly dopamine (DA) transmission. In vivo …
associated with neurotransmission, particularly dopamine (DA) transmission. In vivo …
Neurotensin antagonist acutely and robustly attenuates locomotion that accompanies stimulation of a neurotensin‐containing pathway from rostrobasal forebrain to …
SM Reynolds, S Geisler, A Bérod… - European Journal of …, 2006 - Wiley Online Library
Neurotensin exerts complex effects on the mesolimbic dopamine system that alter motivation
and contribute to neuroadaptations associated with psychostimulant drug administration …
and contribute to neuroadaptations associated with psychostimulant drug administration …
2-Chloro-N-[(S)-phenyl [(2S)-piperidin-2-yl] methyl]-3-trifluoromethyl benzamide, monohydrochloride, an inhibitor of the glycine transporter type 1, increases evoked …
M Leonetti, C Desvignes, I Bougault, J Souilhac… - Neuroscience, 2006 - Elsevier
2-Chloro-NS-phenyl 2S-piperidin-2-yl methyl]-3-trifluoromethyl benzamide,
monohydrochloride (SSR504734) is a potent and selective inhibitor of the glycine …
monohydrochloride (SSR504734) is a potent and selective inhibitor of the glycine …
Ventral midbrain NTS1 receptors mediate conditioned reward induced by the neurotensin analog, D-Tyr [11] neurotensin
K Rouibi, P Bose, PP Rompré, RA Warren - Frontiers in neuroscience, 2015 - frontiersin.org
The present study was aimed at characterizing the mechanisms by which neurotensin (NT)
is acting within the ventral midbrain to induce a psychostimulant-like effect. In a first …
is acting within the ventral midbrain to induce a psychostimulant-like effect. In a first …