Excessive sugar consumption is increasingly considered as a contributor to the emerging
epidemics of obesity and the associated cardiometabolic disease. Sugar is added to the diet …

Molecular networking is a tandem mass spectrometry (MS/MS) data organizational
approach that has been recently introduced in the drug discovery, metabolomics, and …

We found evidence to suggest that insulin resistance plays a potentially key role in the
causal relationship between metabolic syndrome, type 2 diabetes and hyperuricemia …

Uric acid is the metabolic end product of purine metabolism in humans. It has antioxidant
properties that may be protective but can also be pro-oxidant, depending on its chemical …

Sodium/glucose co‐transporter‐2 (SGLT2) inhibitors, which lower blood glucose by
increasing renal glucose elimination, have been shown to reduce the risk of adverse …

Uric acid is the product of purine metabolism. It is known that hyperuricemia, defined as high
levels of blood uric acid, is the major etiological factor of gout. A number of epidemiological …

Background Management of type 2 diabetes with metformin often does not provide
adequate glycemic control, thereby necessitating add-on treatment. In a 24-week clinical …

Uric acid is considered a major antioxidant in human blood that may protect against aging
and oxidative stress. Despite its proposed protective properties, elevated levels of uric acid …

OBJECTIVE Hyperuricemia is strongly associated with obesity and metabolic syndrome and
can predict visceral obesity and insulin resistance. Previously, we showed that soluble uric …

OBJECTIVE To systematically evaluate the association between serum uric acid (SUA) level
and subsequent development of type 2 diabetes. RESEARCH DESIGN AND METHODS We …