Sickle cell disease (SCD) is a group of inherited disorders caused by mutations in HBB,
which encodes haemoglobin subunit β. The incidence is estimated to be between 300,000 …

In July 2022, these guidelines were reviewed by an expert work group convened by ASH.
Review included limited searches for new evidence and discussion of the search results …

Blood transfusion is the most common procedure completed during a given hospitalization
in the United States. Although often life-saving, transfusions are not risk-free. One sequela …

Blood transfusions are life-saving therapies; however, they can result in adverse events that
can be infectious or, more commonly, noninfectious. The most common noninfectious …

Transfusions can be a life-saving treatment of patients with sickle-cell disease (SCD).
However, availability of matched units can be limiting because of distinctive blood group …

A hemolytic transfusion reaction (HTR) is the accelerated clearance or destruction of red
blood cells associated with a transfusion event. Causes of HTRs and differential diagnoses …

Delayed hemolytic transfusion reaction (DHTR) is a life‐threatening complication of
transfusion in sickle cell disease (SCD). The frequency of DHTR is underestimated because …

Delayed hemolytic transfusion reaction (DHTR) is one of the most feared complications of
sickle‐cell disease (SCD). We retrospectively analyzed the clinical and biological features …

BACKGROUND Although red blood cell (RBC) transfusion represents an integral
component of sickle cell disease (SCD) care, transfusion support for some patients can …

Patients with sickle cell disease (SCD) often receive red blood cell (RBC) transfusion
support for the prevention and management of many acute and chronic disease …