Model systems can facilitate and focus research efforts but ill-chosen or inapt ones can
distract or impede scientific progress. In this Opinion article, we pose the question: how can …

The historical roots of the stem cell concept are traced with respect to its usage in
embryology and in hematology. The modern consensus definition of stem cells, comprising …

A near consensus in the philosophy of biology holds that traditional essentialism is a
mistaken view of biological kinds, such as species. Traditional essentialists hold that natural …

An innovative theory proposes a new therapeutic strategy to break the stalemate in the war
on cancer. It is called cancer stem cell (CSC) theory, and Lucie Laplane offers a …

386 relating to auditory perception was found after transplantation of already formed
portions of brain tissue (13). Introduction of human neural progenitor cells into developing …

Biologists use models in two distinct ways that have not been clearly articulated. A model
may be used either as an exemplar of a larger group, or as a surrogate for a specific target …

This examination of stem cell biology from a philosophy of science perspective clarifies the
field's central concept, the stem cell, as well as its aims, methods, models, explanations and …

Early in his career Thomas Hunt Morgan was interested in embryology and dedicated his
research to studying organisms that could regenerate. Widely regarded as a regeneration …

Indeterminate growth, the life-long growth without fixed limits, is typical of some
evolutionarily very successful aquatic invertebrate groups such as the decapod crustaceans …

The potential use of stem cells in regenerative medicine requires the ability to be able to
control stem cell fate as cellular networks are developed. Here, nanodiamonds (≈ 10 nm) …