Whispering-gallery-mode biosensing: label-free detection down to single molecules

F Vollmer, S Arnold - Nature methods, 2008 - nature.com
Optical label-free detectors, such as the venerable surface plasmon resonance (SPR)
sensor, are generally favored for their ability to obtain quantitative data on intermolecular …

Spherical whispering‐gallery‐mode microresonators

A Chiasera, Y Dumeige, P Feron… - Laser & Photonics …, 2010 - Wiley Online Library
Whispering‐gallery modes (WGM) on a spherical surface were first described by Lord
Rayleigh at the beginning of the last century, but only after the invention of laser did they …

Phase-matched excitation of whispering-gallery-mode resonances by a fiber taper

JC Knight, G Cheung, F Jacques, TA Birks - Optics letters, 1997 - opg.optica.org
We show that high-Q whispering-gallery modes in fused-silica microspheres can be
efficiently excited by an optical fiber taper. By adjusting the taper diameter to match the …

Protein detection by optical shift of a resonant microcavity

F Vollmer, D Braun, A Libchaber, M Khoshsima… - Applied physics …, 2002 - pubs.aip.org
We present an optical biosensor with unprecedented sensitivity for detection of unlabeled
molecules. Our device uses optical resonances in a dielectric microparticle (whispering …

[PDF][PDF] Optical resonators with whispering-gallery modes-part I: basics

AB Matsko, VS Ilchenko - IEEE Journal of selected topics in …, 2006 - qolwiki.physics.wm.edu
Optical Resonators With Whispering-Gallery Modes—Part I: Basics Page 1 IEEE JOURNAL OF
SELECTED TOPICS IN QUANTUM ELECTRONICS, VOL. 12, NO. 1, JANUARY/FEBRUARY …

Optical microsphere resonators: optimal coupling to high-Q whispering-gallery modes

ML Gorodetsky, VS Ilchenko - JOSA B, 1999 - opg.optica.org
A general model is presented for coupling of high-Q whispering-gallery modes in optical
microsphere resonators with coupler devices that possess a discrete and continuous …

Shift of whispering-gallery modes in microspheres by protein adsorption

S Arnold, M Khoshsima, I Teraoka, S Holler, F Vollmer - Optics letters, 2003 - opg.optica.org
Biosensors based on the shift of whispering-gallery modes in microspheres accompanying
protein adsorption are described by use of a perturbation theory. For random spatial …

Analytic theory of coupling from tapered fibers and half-blocks into microsphere resonators

BE Little, JP Laine, HA Haus, L Fellow - Journal of lightwave …, 1999 - opg.optica.org
Coupling from tapered fibers and polished half-block couplers into the high-Q whispering
gallery modes of microsphere resonators is investigated analytically. Numerous formulas …

Label-free optical resonant sensors for biochemical applications

C Ciminelli, CM Campanella, F Dell'Olio… - Progress in Quantum …, 2013 - Elsevier
For a number of years, the scientific community has been paying growing attention to the
monitoring and enhancement of public health and the quality of life through the detection of …

Surface-roughness-induced contradirectional coupling in ring and disk resonators

BE Little, JP Laine, ST Chu - Optics letters, 1997 - opg.optica.org
Reflections that are due to random surface roughness in periodic structures such as
dielectric rings and disks inherently phase match forward-and backward-propagating …