Passive, active and endogenous organ-targeted lipid and polymer nanoparticles for delivery of genetic drugs

SA Dilliard, DJ Siegwart - Nature Reviews Materials, 2023 - nature.com
Genetic drugs based on nucleic acid biomolecules are a rapidly emerging class of
medicines that directly reprogramme the central dogma of biology to prevent and treat …

Where is nano today and where is it headed? A review of nanomedicine and the dilemma of nanotoxicology

C Domingues, A Santos, C Alvarez-Lorenzo… - ACS …, 2022 - ACS Publications
Worldwide nanotechnology development and application have fueled many scientific
advances, but technophilic expectations and technophobic demands must be …

Emerging technologies in multi‐material bioprinting

H Ravanbakhsh, V Karamzadeh, G Bao… - Advanced …, 2021 - Wiley Online Library
Bioprinting, within the emerging field of biofabrication, aims at the fabrication of functional
biomimetic constructs. Different 3D bioprinting techniques have been adapted to bioprint cell …

Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment

G Huang, F Li, X Zhao, Y Ma, Y Li, M Lin, G Jin… - Chemical …, 2017 - ACS Publications
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

Multisensor-integrated organs-on-chips platform for automated and continual in situ monitoring of organoid behaviors

YS Zhang, J Aleman, SR Shin, T Kilic… - Proceedings of the …, 2017 - National Acad Sciences
Organ-on-a-chip systems are miniaturized microfluidic 3D human tissue and organ models
designed to recapitulate the important biological and physiological parameters of their in …

Bioprinting 3D microfibrous scaffolds for engineering endothelialized myocardium and heart-on-a-chip

YS Zhang, A Arneri, S Bersini, SR Shin, K Zhu… - Biomaterials, 2016 - Elsevier
Engineering cardiac tissues and organ models remains a great challenge due to the
hierarchical structure of the native myocardium. The need of integrating blood vessels brings …

[HTML][HTML] Organ-on-a-chip: a survey of technical results and problems

AE Danku, EH Dulf, C Braicu, A Jurj… - … in bioengineering and …, 2022 - frontiersin.org
Organ-on-a-chip (OoC), also known as micro physiological systems or 'tissue chips' have
attracted substantial interest in recent years due to their numerous applications, especially in …

Evolution of biochip technology: A review from lab-on-a-chip to organ-on-a-chip

N Azizipour, R Avazpour, DH Rosenzweig, M Sawan… - Micromachines, 2020 - mdpi.com
Following the advancements in microfluidics and lab-on-a-chip (LOC) technologies, a novel
biomedical application for microfluidic based devices has emerged in recent years and …

A decade of progress in tissue engineering

A Khademhosseini, R Langer - Nature protocols, 2016 - nature.com
Tremendous progress has been achieved in the field of tissue engineering in the past
decade. Several major challenges laid down 10 years ago, have been studied, including …

Diverse applications of nanomedicine

B Pelaz, C Alexiou, RA Alvarez-Puebla, F Alves… - ACS …, 2017 - ACS Publications
The design and use of materials in the nanoscale size range for addressing medical and
health-related issues continues to receive increasing interest. Research in nanomedicine …