[HTML][HTML] The role of the circadian system in the etiology of depression

M de Leeuw, SI Verhoeve, NJA van der Wee… - Neuroscience & …, 2023 - Elsevier
Circadian rhythms have evolved in almost all organisms enabling them to anticipate
alternating changes in the environment. As a consequence, the circadian clock controls a …

Circadian disruptions and brain clock dysregulation in mood disorders

J Mendoza - Nature Mental Health, 2024 - nature.com
The circadian system, composed of a network of brain and peripheral 24-hour clocks and
oscillators, allows organisms to anticipate and synchronize to natural daily events. The day …

The sleep–circadian interface: A window into mental disorders

N Meyer, R Lok, C Schmidt, SD Kyle… - Proceedings of the …, 2024 - National Acad Sciences
Sleep, circadian rhythms, and mental health are reciprocally interlinked. Disruption to the
quality, continuity, and timing of sleep can precipitate or exacerbate psychiatric symptoms in …

Short-term acute bright light exposure induces a prolonged anxiogenic effect in mice via a retinal ipRGC-CeA circuit

G Wang, YF Liu, Z Yang, CX Yu, Q Tong, YL Tang… - Science …, 2023 - science.org
Light modulates mood through various retina-brain pathways. We showed that mice treated
with short-term acute bright light exposure displayed anxiety-related phenotypes in a …

Artificial light at night, MRI-based measures of brain iron deposition and incidence of multiple mental disorders

J Jin, W Han, T Yang, Z Xu, J Zhang, R Cao… - Science of the Total …, 2023 - Elsevier
Background Epidemiologic evidence on whether iron accumulation in brain modified the
association between artificial light at night (ALAN) and incident mental disorders is lacking …

Time to learn: The role of the molecular circadian clock in learning and memory

CW Smies, KK Bodinayake, JL Kwapis - Neurobiology of learning and …, 2022 - Elsevier
The circadian system plays an important role in aligning biological processes with the
external time of day. A range of physiological functions are governed by the circadian cycle …

[HTML][HTML] Cigarette smoke-induced pulmonary impairment is associated with social recognition memory impairments and alterations in microglial profiles within the …

SN De Luca, SMH Chan, A Dobric, H Wang… - Brain, Behavior, and …, 2023 - Elsevier
Chronic obstructive pulmonary disease (COPD) is a major, incurable respiratory condition
that is primarily caused by cigarette smoking (CS). Neurocognitive disorders including …

Altered expression of somatostatin signaling molecules and clock genes in the hippocampus of subjects with substance use disorder

J Valeri, SM O'Donovan, W Wang, D Sinclair… - Frontiers in …, 2022 - frontiersin.org
Substance use disorders are a debilitating group of psychiatric disorders with a high degree
of comorbidity with major depressive disorder. Sleep and circadian rhythm disturbances are …

Disrupted circadian rhythms and mental health

WH Walker II, JC Walton, RJ Nelson - Handbook of clinical neurology, 2021 - Elsevier
During the evolution of life, the temporal rhythm of our rotating planet was internalized in the
form of circadian rhythms. Circadian rhythms are~ 24 h internal manifestations that drive …

The real-world association between digital markers of circadian disruption and mental health risks

MP Lee, DW Kim, Y Fang, R Kim, ASB Bohnert… - NPJ Digital …, 2024 - nature.com
While circadian disruption is recognized as a potential driver of depression, its real-world
impact is poorly understood. A critical step to addressing this is the noninvasive collection of …